Paeds Gastro Flashcards
1
Q
Coeliac autoantibodies
A
Tissue transglutaminase antibodies (anti TTG)
Endomysial antibodies (EMAs)
Deaminated gliadin peptides antibodies (anti-DPGs)
2
Q
What also needs to be tested when screening for coealiac autoantibodies
A
Total IgA levels to rule out IgA deficiency (anti TTG and EMA are IgA so in a deficiency would be false neg)
3
Q
What would intestinal biopsy show in coeliac
A
Crypt hypertrophy
Villous atrophy
4
Q
Derm feature of coeliac
A
Dermatitis herpetiformis
5
Q
HLA associated with coeliac
A
HLA-DQ2 (90%)
HLA-DQ8
6
Q
Laxatives for disimpaction regime
A
Movicol first line escalating dose Over 2 weeks
Add senna if unresponsive
7
Q
Maintenance laxative tx
A
Movicol
Dietary changes
