Oxyhaemoglobin Dissociation Curve Flashcards
Association
When o2 combines with haemoglobin through diffusion at the lungs to give oxyhaemoglobin
saturated
The amount of O2 combined with haemoglobin usually expressed as % and depends on ppO2. Haemoglobin Is 100% saturated at the lungs
Dissociation
When o2 releases from haemoglobin through diffusion at the muscles
Oxyhaemoglobin dissociation curve
Shows us the relationship between ppO2 and % saturation of haemoglobin
Affinity
How much the o2 wants to associate. O2 will associate slowly to start with and then increase with speed
Look at
Curve
What happens as more o2 molecules associates
Affinity increases
Bohr shift
During exercise more O2 dissociates from the haemoglobin because of an increase in CO2. This forces off the O2 and reduces its affinity
Two other factors that increase dissociation
Body temperature increases, O2 is more likely dissociate from the haemoglobin
Acidity- lactic and carbonic acid increases acidity in the blood
Makes o2 more likely to dissociate haemoglobin