Oxazolidinones Flashcards

1
Q

Linezolieمیکانزم عمل

A

Bind to 23S site of 50S subunit

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2
Q

Bacteriostatic but bactericidal against …………

A

Streptococcal species

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3
Q

بصورة عامة ضد

A

گرام پوزتڤ

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4
Q

ممتاز orally

A

كأنما IV
صد در صد bioavailability

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5
Q

Enterococcus faecium + staphylococcal infections
التي تقاوم ڤانكومايسن

A

Linezolid (Oxazolidinone)
Streptogramines

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6
Q

أعراض جانبية

A

1/Serotonin syndrome

٢/قلة الصفائح الدموية شائع جدا ،وممكن قلة RBC و النوتروفيلات ايضا.
لاین زولد یحد حد للصفائح الدمویه

٣/ اعتلال العصب البصري والمحيطي. لاین زولد کورکه د

4/ lactic acidosis
لاین زولد یحب ترشی

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7
Q

ماهو الجميل في التيدي زولد

A

لاحاجة لتغير الجرعة في hepatic+renal impairment

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8
Q

استخدامات تيدي زولد

A

1/MRSA
2/Vancomycin -resistant Enterococci
3/streptococci

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9
Q

Which one longer half life
لاين زولد او تيدي زولد

A

تيدي زولد لأنه جديد الأختراع🤪

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