Osmosis Questions

Question 1

Vincristine + Mechlorethamine + Procarbazine + Pednisone = Tx for what?

Answer 1

Hodgkin Disease

Question 2

Name the standard 4-drug therapy for ALL.

Answer 2

Vincristine, Daunorubicin, Asparagine, and Prednisone

Question 3

All-trans-retinoic acid is used for what?

Answer 3

AML

Question 4

How long is an apneic episode in a newborn?

Answer 4

At least 20 seconds, or with significant oxygen desaturation or bradycardia

Question 5

What is the MOA of caffeine therapy to treat apnea of prematurity?

Answer 5

Methylxanthines inhibit adenosine receptors (act as stimulant: increase heart rate, stimulate respiration)

Question 6

What type of rash can be caused by Amoxicillin?

Answer 6

Erythema Multiforme

Question 7

What drugs are known to trigger erythema multiforme?

Answer 7

Amoxicillin, Penicillin, Cephalosporins, Macrolides, Sulfonamides

Question 8

What kind of anemia results from renal failure?

Answer 8

Normochromic/Normocytic (decreased EPO production from kidneys)

Question 9

Meningitis + Petechiae = ?

Answer 9

Neiserria meningitis

Question 10

1 cause of meningitis in all ages except neonates = ?

Answer 10

Strep pneumo

Question 11

1 cause of meningitis in neonates = ?

Answer 11

GBS

Question 12

Meconium ileus of newborn = ?

Answer 12

Cystic Fibrosis

Question 13

What type of brain tumors are common for tuberous sclerosis?

Answer 13

Cortical tuber; Subependymal nodules; Giant-cell astrocytomas

Question 14

What type of brain tumor is NOT common for tuberous sclerosis?

Answer 14

Medulloblastoma = not common with TS

Question 15

Active boy 12-15 yo with swelling and pain over tibial tubercle without knee joint involvement.

Answer 15

Osgood-Schlatter Disease

Question 16

What is the leading cause of accidental injury in a child age 1-4?

Answer 16

Drowning

Question 17

Respiratory depression + Vomiting + Hypoglycemia = ?

Answer 17

Alcohol ingestion

Question 18

Idiopathic Avascular Necrosis in a boy 5-10 yo?

Answer 18

Legg-Calve-Perthes disease

Question 19

Heel pain worse with first steps in the morning

Answer 19

Plantar fasciitis

Question 20

Define Sever Disease

Answer 20

Inflammation of the calcaneal growth plate; runners that experience heel pain and sweeling at the Achilles tendon.

Question 21

What is appropriate treatment for a hemangioma?

Answer 21

No treatment indicated if not on comsetically sensitive area; If on face apply topical corticosteroid or topical timolol

Question 22

What is the most common location of an intussusception?

Answer 22

Ileocecal valve

Question 23

Abdominal pain + bilious vomiting + currant jelly stool = ?

Answer 23

Intussusception

Question 24

Differentiate testicular torsion and epididymitis.

Answer 24

Epididymitis = increased blood flow with positive cremasteric reflex; Testicular torsion = ischemia with negative cremasteric reflex