oral biofilms Flashcards
what is a biofilm?
matrix-enclosed bacterial populations adherent to each other and/or to surfaces or interfaces
what are the defining characteristic of biofilms?
defence
favourable habitat
community
default mode
what are the stages of biofilm development?
adhesion, colonization accumulation complex community dispersal
what are the benefits of biofilms?
protective environment co-ordinated cellular events division of labour EPS traps nutrients less energy utilised survival in numbers
what is glycocalyx?
ECM composed of exopolymeric substrate
maintains a hydrated environment
microcolonies within are organised, allowing active diffusion
provides protective barrier- immune factors and antibiotics
what is dental plaque?
a diverse microbial community found on the tooth surface, embedder in a matric of polymers of bacterial and salivary origin
what are 5 oral biofilm diseases?
caries-coronal and root surface endodontic infections periodontal infections oral malodour mucosal infections-thrush, angular cheilitis, denture stomatitis
what are the stages of plaque development?
colonisation by pioneer bacteria
outgrowth
secondary colonisation
climax community
what are the stages of caries progression?
adhesion survival + growth biofilm formation complex plaque acid caries
what effect can a high protein diet have on oral biofilm?
few acidogenic organisms-ammonia produced
more gram -
secondary metabolites-malodour
what effect can a high carb diet have on oral biofilm?
metabolism reduced pH
aciduric organisms thrive
streptococci + lactobacilli