Opthamology

Question 1

MOA and class Latanoprost

Answer 1

Prostaglandin analogue, increases uveoscleral outflow. May cause brown pigmentiation of irisand increased eyelash length

Question 2

MOA and class Timolol and betaxolol

Answer 2

Beta blockers: Reduce aqueous production

Question 3

MOA and class of brimonidine

Answer 3

Sympathomimetics, alpha 2 adrenoreceptor agonist: reduces aqueous produciton and increases outflow: dont take with MOAi or tricyclics

Question 4

MOA and class of Dorzolamide

Answer 4

Cabonic anhydrase inhibitor reduced aqueous production.

Question 5

NMOA and class of Pilocarpine

Answer 5

Muscarinic receptor agonist: increase uveoscleral outflow. Constricted pupil, blurred vision on occasion.

Question 6

Definition of glaucoma

Answer 6

Optic neuropathy: rasie intraoccular pressure.
The split in definiton open vs. closed angle is whether the iris is covering the trabecular meshwork of the peripheral iris.

Question 7

Treatment tier of glaucoma

Answer 7

NICE guidelines:
first line: prostaglandin analogue (PGA) eyedrop
second line: beta-blocker, carbonic anhydrase inhibitor, or sympathomimetic eyedrop
if more advanced: surgery or laser treatment can be tried2