Obsessive-Compulsive Disorder Flashcards
Rapoport (1989)
Early onset OCD in Charles. Charles was doing well before his OCD symptoms started to take up most of his time and his family functioning was disrupted.
Charles was given a tricyclic antidepressant and relapsed after a month. He became tolerant to the drug.
Early onset OCD in Charles. Charles was doing well before his OCD symptoms started to take up most of his time and his family functioning was disrupted.
Charles was given a tricyclic antidepressant and relapsed after a month. He became tolerant to the drug.
Rapoport (1989)
Hodgson and Rachman (1977)
50 students completed the MOCI and were reassessed one month later. MOCI was shown to have high test-retest reliability.
50 students completed the MOCI and were reassessed one month later. MOCI was shown to have high test-retest reliability.
Hodgson and Rachman (1977)
Goodman et al. (1989a)
40 people with OCD completed YBOCS, assessed by four different interviewers. There was excellent agreement (high inter-rater reliability).
40 people with OCD completed YBOCS, assessed by four different interviewers. There was excellent agreement (high inter-rater reliability).
Goodman et al. (1989a)
Carey and Gottesman (1981)
The concordance rate for OCD is 87% in MZ and 47% in DZ. This suggests that OCD is one of the most heritable of all mental disorders.
The concordance rate for OCD is 87% in MZ and 47% in DZ. This suggests that OCD is one of the most heritable of all mental disorders.
Carey and Gottesman (1981)
Millet et al. (2003)
Allele 2 of the DRD4 gene that codes for D4 receptor appears to be less common in people with OCD.
Allele 2 of the DRD4 gene that codes for D4 receptor appears to be less common in people with OCD.
Millet et al. (2003)
Shmelkov et al. (2010)
Artificially silencing the SLITRK3 gene in mice made them display compulsive grooming and bury marbles placed in their cages, a behaviour similar to hoarding seen in some humans with OCD.
Artificially silencing the SLITRK3 gene in mice made them display compulsive grooming and bury marbles placed in their cages, a behaviour similar to hoarding seen in some humans with OCD.
Shmelkov et al. (2010)
Humble et al. (2013)
Higher levels of oxytocin are associated with more severe OCD symptoms, particularly in people who develop the condition at a young age and are resistant to drug treatments.
Higher levels of oxytocin are associated with more severe OCD symptoms, particularly in people who develop the condition at a young age and are resistant to drug treatments.
Humble et al. (2013)
Lopatka and Rachman (1995)
30 people with “checking-type” OCD reported less urge to check and less distress compared to the non-OCD control group when told that they would not be held responsible for any negative outcomes.
