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Microbiology > Non-Renal Elimination > Flashcards

Non-Renal Elimination Flashcards

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1
Q

D(q)crimes

A

Doxycycline - hepatic excretion

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2
Q

d(Q)crimes

A

Quinolones - Ciprofloxacin IS renally eliminated, but inhibits P450 (caffeine-theophylline)

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3
Q

d(q)Crimes

A

Clindamycin - hepatic excretion

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4
Q

d(q)cRimes

A

Rifampin - P450 inducer - potentially hepatotoxicity

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5
Q

d(q)crImes

A

Isoniazid - genetic polymorphism of N-acetyl transferase metabolism, potential hepatoxicity

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6
Q

d(q)criMes

A

Metronidazole - DDI with alcohol due to inhibition of aldehyde metabolism (Antabuse reaction)

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7
Q

d(q)crimEs

A

Erythromycin/Clarithromycin - DDI due to inhibition of P450

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8
Q

d(q)crimeS

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Sulfonamides - N-acetylated to more lipid-soluble metabolite - concern for renal crystalluria

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Microbiology (15 decks)

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