Nicotinic Antagonists Flashcards

1
Q

What is the mechanism of nicotinic antagonists?

A
  • prevent endogenous ACh Binding and subsequent muscle cell depolarization.
  • called “non-depolarizing blockade”
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2
Q

Which nicotinic antagonist causes “flaccid paralysis”?

A
  • Tubocurare
  • think flaccid like a TUB-O-lard
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3
Q

What drug are used in the treatment of aortic dissection to lower BP?

A
  • Mecamylamine
  • Trimethaphan
  • Think Aortic dissection is the MECA of bad days
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