NEW SPMM Flashcards
RADIAL ARM TEST
T MAZE TEST
MORRIS WATER NAVIGATION TEST
Latent inhibition test
Yoked shock test b
Behavioural despair test /Porsolt test/Forced swimming
The light/dark box test
The elevated plus maze
The radial arm maze by Olton and Samuelson in 1976 measure spatial learning and memory in rats.
The T-maze
spatial learning and memory in rodents.
The Morris water navigation task
to study spatial learning and memory. developed by Richard G. Morris in 1981 to show that hippocampal lesions impaired spatial learning.
Latent inhibition test
for sensorimotor gating. Latent inhibition is defined as an animal’s unconscious capacity to ignore stimuli that experience has shown is irrelevant to its needs.
Yoked shock test
‘Learned helplessness’, model for depression.
Behavioural despair test /Porsolt test/Forced swimming tused to measure the effect of antidepressant drugs on the behaviour of laboratory animals (typically rats or mice).
The light/dark box test (EXPLORATORY ACTIVITY)
anxiety-related behaviour (Crawley)
useful to predict anxiolytic-like or anxiogenic-like activity in mice. Classic anxiolytics (benzodiazepines), as well as the newer anxiolytic-like compounds (e.g. serotonergic drugs or drugs acting on neuropeptide receptors), can be detected using this paradigm. It has the advantages of being quick and easy to use, without requiring the prior training of animals.
The elevated plus maze
anxiety-like behavior (fear/anxiety).
mouse is placed in the center of the maze and the number of entries and amount of time spent in the open and closed arms are recorded during a brief trial.
