Neurotransmitters in NS Flashcards
1
Q
What is the main excitatory nt?
A
- Glutamate [works in the CNS]
2
Q
What receptors does glutamate have?
A
- (cation) ionotropic: AMPA, NMDA kainate receptors
- metabotropic: mGlu1-8
3
Q
What is the main inhibitory nt?
A
- GABA [works in the CNS]
4
Q
What receptors does GABA have?
A
- (anion) inotropic: GABAa
- metabotropic: GABAb
5
Q
What nts have only metabotropic receptors?
A
- Dopamine [D1-5]
- Noradrenaline [alpha1-2, beta1-3]
6
Q
What receptors does dopamine have?
A
- D1-5
(all metabotropic)
7
Q
What receptors does noradrenaline have?
A
- alpha1-2
- beta1-3
(all metabotropic)
8
Q
What are metabotropic receptors?
A
- G protein coupled
9
Q
What receptors does serotonin (5-HT) have
A
- (cation) ionotropic: 5-HT3
- metabotropic: 5-HT1, 2, 4-7
10
Q
What receptors does acetylcholine have?
A
- (cation) ionotropic: nAChRs
- metabotropic: mAChRs
