Neuroplasticity

Question 1

Define neuroplasticity

Answer 1

ability of nervous system to reorganize/rewire its structure and function in response to internal or external stimuli

Question 2

Define long term potentiation

Answer 2

LTP is a long lasting strengthening of a synaptic connection that occurs with repeated stimulation

Question 3

What two receptors does glutamate bind to? What is their effect?

Answer 3

AMPA and NMDA

Depolarization

Question 4

What are the 3 effects of LTP on a synaptic level?

Answer 4

Phosphorylation of AMPA receptors
Creation of new AMPA receptors
Sprouting of dendrites

Question 5

Define long term depression

Answer 5

Reverse process that can weaken the efficacy of the synapse

Question 6

What is the neuroplasticity derived proposed therapy for stroke?

Answer 6

Constraint induced therapy

Question 7

What are the three areas involved in pleasure control?

Answer 7

Prefrontal cortex inhibits nucleus accumbance

Nucleus accumbance stimulates ventral tegnmental area to release dopamine

Question 8

What is the effect of continued use of drug/addiction?

Answer 8

loss of inhibition of prefrontal cortex

Question 9

What are the two types and subtypes of transcranial magnetic stimulation?

Answer 9

Single TMS, multiple TMS
Multiple: high frequency–> stimulates
Low frequency–> supresses

Question 10

What are the possible side effects of TMS?

Answer 10

Some case reports of seizures