Neurology

Question 1

Define seizure

Answer 1

Hypersynchronous activity of the brain

Question 2

What’s considered a RESPONDER in seizure treatment?

Answer 2

is a patient that has experienced at least a 50% reduction in seizure frequency following the addition of a specific antiseizure intervention (e.g. addition of a new drug)

Question 3

Define Refractory epileptic patient

Answer 3

is a dog who has poor seizure control, despite documented evidence of plasma drug concentrations of two or more typically effective antiseizure drugs that are within what is considered the therapeutic range

Question 4

Whats is percentage of dogs that are Refractory epileptic?

Answer 4

25-30%

Question 5

Define Kindling (seizures)

Answer 5

refers to recruitment over time of previously nonhyperexcitable neurons into a group of hyperexcitable neurons (the seizure focus) via constant stimulation of these neurons by the seizure focus within a cerebral hemisphere

Question 6

Define Mirroring

Answer 6

involves recruitment of neurons into the seizure focus from the opposite cerebral hemisphere via the corpus callosum