Neuro Test 1 Flashcards

1
Q

The three small molecule neurotransmitters are: ___, ___ and ___. ___ is excitatory, ___ is inhibitory and ___ can be either

A

Glutamate
GABA
ACh

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2
Q

The three monoamines are ___, ___/___ and ___ and they are all ___

A

Dopamine
Norepinephrine/ epinephrine
Serotonin

Excitatory

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3
Q

The two neuropeptides are ___ and ___

A

ACTH

Substance P

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4
Q

___ is associated with Parkinson’s

A

Dopamine

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5
Q

___ is associated with depression

A

Serotonin

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6
Q

The primary motor cortex is located in the ___ ___

A

Precentral gyrus

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7
Q

The frontal lobe deals mostly with ___ function but also has ___ and ___ functions

A

Motor
Executive
Speech

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8
Q

The primary somatosensory cortex is in the ___ ___

A

Postcentral gyrus

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9
Q

The parietal lobe deals mainly with ___ functions, but also deals with ___ and ___

A

Sensory
Language
Directions

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10
Q

The primary auditory cortex is located in the ___ ___

A

Temporal lobe

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11
Q

The temporal lobe is the main lobe for ___ functions and also deals with higher order ___ processing and ___ and ___

A

Auditory
Visual
Learning
Memory

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12
Q

The primary visual cortex is located in the ___ ___ in the ___ lobe

A

Calcarine sulcus

Occipital lobe

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13
Q

The limbic lobe deals with ___, drive related behaviors and ___

A

Emotions

Memory

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14
Q

The term limbic comes from the Latin word __ meaning ___

A

Limbus

Border

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15
Q

The four divisions of the diencephalon are the:

A

Thalamus
Hypothalamus
Epithalamus
Subthalamus

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16
Q

The thalamus is known as the ___ ___ ___

A

Air traffic controller

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17
Q

___ is the only sense that doesn’t stop in the thalamus

A

Olfaction

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18
Q

The ___ is the major visceral control center

A

Hypothalamus

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19
Q

The ___ ___ connects the ___ with the pituitary

A

Infundibular stalk

Hypothalamus

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20
Q

The major components of the basal ganglia are the ___, ___, and the ___ ___

A

Caudate
Putamen
Globus pallidus

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21
Q

The basal ganglia is involved in ___ ___

A

Movement control

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22
Q

The two cranial nerves to bypass the brainstem are

A

I and II

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23
Q

12 cranial nerves

A
Olfactory
Optic
Oculomotor
Trochlear
Trigeminal
Abducens
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory
Hypoglossal
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24
Q

The CN’s associated with the midbrain are:

A

III and IV

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25
Q

The CN associated with the pons (from rostral to caudal) are:

A

V, VI, VII, VIII

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26
Q

The CN associated with the medulla (from rostral to caudal) are:

A

IX, X, XI, XII

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27
Q

The ___ ___ separates the cerebral hemispheres and the ___ ___ separates the cerebrum and the cerebellum

A

Falx cerebri

Tentorium cerebelli

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28
Q

Herniations occur when ___ ___ increases

A

Intracranial pressure

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29
Q

Difference between epidural and subdural hemorrhages

A

Epidural is a tear of meninges love arteries (blood b/t skull and dura)

Subdural is tear of bridging veins (innermost dural layer)

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30
Q

Superficial veins of the head empty into ___ ___ ___ while deep veins empty into ___ ___

A

Superior sagittal sinus

Straight sinus

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31
Q

The vertebral arteries fuse to become the ___ ___ at the ___

A

Basilar artery

Pons

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32
Q

PICA supplies inferior ___ and lateral ___

A

Cerebellum

Medulla

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33
Q

BA bifurcates at the ___ into 2 ___ ___ ___

A

Midbrain

P C As

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34
Q

AICA and SCA come off of the ___ artery

A

Basilar

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35
Q

AICA supplies anterior inferior surface of ___ and caudal ___

A

Pons

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36
Q

SCA supplies superior ___, ___ midbrain and ___ ___

A

Cerebellum
Caudal midbrain
Rostral pons

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37
Q

___ ___ substances can go through the BBB

A

Lipid soluble

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38
Q

How does glucose cross BBB

A

Through facilitated diffusion

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39
Q

Derivatives of the neural crest (9)

A
VEAL TO GAG
Viscerocranium
Enteric / ANS (post ganglionic)
Leptomeninges
Trunks of great vessels
Odontoblasts
Ganglia
Adrenal medulla
Glial Cells
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40
Q

The spinal cord is first formed by ___ cells. Once the neural tube closes they will differentiate to become ___ that will help form the ___ layer

A

Neuroepithelium
Neuroblasts
Mantle

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41
Q

The layers of the spinal cord are (from deep to superficial) are:

A

Neuroepithelial layer
Mantle layer
Marginal layer

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42
Q

In the spinal cord, neuroepithelial cells can become ___ or ___ cells. The ___ can further become ___ or oligodendroglia

A

Neuroepithelial
Gliablast or ependymal
Gliablasts
Astrocyte

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43
Q

Microglia come from ___ ___ cells

A

Vascular mesenchymal

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44
Q

___ cells myelinate in the CNS and ___ cells myelinate in the PNS

A

Oligodendroglia

Schwann

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45
Q

In adults, the spinal cord terminates around _ _ and the dura terminates at _ _

A

L2

S2

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46
Q

6 nerve modalities and definition of each

A

Somatic Efferent - skeletal muscles (except from pharyngeal arches)
Special Visceral Efferent - skeletal from pharyngeal arches (except XI)
General Visceral Efferent - ANS
Somatic Afferent - touch, temp, pain
Special Afferent - taste, smell, vision, hearing, balance
General Visceral Afferent - Interoceptive info

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47
Q

From out to in, the modalities go ___, ___ ___, ___ ___

A

Somatic
Special visceral
General visceral

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48
Q

In the midbrain, the alar plate forms the ___

A

Colliculi

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49
Q

The pituitary gland is formed from the ___ and ___ ___

A

Infundibulum

Rathke’s Pouch

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50
Q

The adrenal cortex is derived from ___

A

Mesoderm

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51
Q

If the neural tube doesn’t close in the cranial region, it is called ___ but if it is in the spinal region it is called ___ ___

A

Anencephaly

Spina bifida

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52
Q

Spina bifida can be hidden (___) or can be with the spinal cord protruding (___) or with the subarachnoid space posterior to the cord protruding (___)

A

Occulta
Meningomyelocele
Meningocele

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53
Q

Muscles can have ___ ___ that detect muscle length and ___ ___ ___ that detect muscle tension

A

Muscle spindles

Golgi tendon organs

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54
Q

The two enlargements of the spinal cord are in the ___ and ___ region because of nerves coming from the ___ and ___

A

Cervical and lumbar

Arms and legs

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55
Q

The posterior intermediate sulcus is only found above level _ _

A

T6

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56
Q

In the anterior horn, the clusters of neurons that control axial muscles are more ___ and those that control limb muscles are more ___

A

Medial

Lateral

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57
Q

The anterior horn at cervical levels contains the ___ ___ ___ and the ___ ___

A

Spinal accessory nucleus

Phrenic nucleus

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58
Q

Difference between somatic and autonomic

A

Sympathetic and parasympathetic don’t reach targets directly. They have a 2-neuron chain

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59
Q

Which autonomic part uses norepinephrine instead of ACh

A

Postganglionic axon of sympathetic

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60
Q

White communicating rami are from __ to __

A

T1 to L2/3

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61
Q

Sympathetic fibers reach the head through the ___ ___ and the ___ ___

A

Cervical ganglia

Carotid plexus

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62
Q

Referred pain happens when ___ ___ and ___ ___ are innervated by the same cord level

A

Visceral structure

Surface structure

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63
Q

Three special characteristics of neurons

A

Extreme longevity
Amitotic
High metabolic rate

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64
Q

Nissl body is ___ ___ ___ and ___ and are visualized by ___ stain

A

RER and Ribosomes

Hematoxylin

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65
Q

From least to most common, the three types of neurons are

A

Bipolar neuron
Unipolar neuron
Multipolar neuron

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66
Q

Most interneurons are ___ neurons

A

Multipolar

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67
Q

5 types of synapses

A
Axodendritic
Axosomatic
Axoaxonic
Dendrodendritic
Dendrosomatic
68
Q

Three ways neurotransmitters can be removed from receptor

A

Degradation by enzymes
Reuptake by astrocytes or presynapse
Diffusion away

69
Q

5 types of neuroglia

A
SAME-O
Schwann
Astrocytes
Microglia
Ependymal
Oligodendrocyte
70
Q

Astrocytes have ___ ___ that surround ___

A

Perivascular feet

Vessels

71
Q

___ cells line ventricles

A

Ependymal

72
Q

___ have elongated nuclei

A

Microglia

73
Q

Schwann cells are found in ___ and oligodendrocytes are found in ___. Of the two, ___ can myelinate multiple axons at the same time, while ___ can only myelinate part of one axon

A

PNS
CNS
Oligodendrocytes
Schwann (remember, one Schwann cell can surround multiple axons at the same time, but it’s just for support)

74
Q

___ cells ride on neuronal cell bodies

A

Satellite

75
Q

In CNS, neuronal cell bodies are called ___ and neuronal axons are called ___

In PNS, neuronal cell bodies are called ___ and neuronal axons are called ___

A

Nuclei and tract

Ganglia and nerve

76
Q

___ ___ is used to see myelin sheath well

A

Osmium tetroxide

77
Q

Three functions of brainstem

A

Conduit
Cranial nerve
Integrative

78
Q

The RF helps regulates (6 things)

A
Posture
Stereotypic motor behaviors
Regulating internal environment
Pain regulation
Sleep and wakefulness
Emotional tone
79
Q

The two reticulospinal tracts are the medial (___) and the lateral (___)

A

Pontine

Medullary

80
Q

How is the RF related to the corticospinal tract

A

It is an alternative to the CST

81
Q

The RF is associated with ___ generators

A

Pattern

82
Q

RF can do what to pain signals

A

Suppress or facilitate

83
Q

In the RF, Norepinephrine is found in the ___ nucleus (of the medulla) and the ___ ___ (of the rostral pons)

A

Solitary

Locus ceruleus

84
Q

Norepinephrine in the trigeminal nucleus and spinal cord is made in the ___ medulla

A

Ventrolateral

85
Q

Lack of norepinephrine is related to ___

A

Depression

86
Q

Why do Parkinson’s disease patients often have depression?

A

Locus ceruleus neurons are lost in Parkinson’s

87
Q

Dopamine is made in the ___ ___ and the ventral tegmental area

A

Substantia nigra

88
Q

Schizophrenia is associated with what part of the brain and what chemical

A

Ventral tegmental area

Dopamine

89
Q

With schizo, too low dopamine causes ____ ___ and too much dopamine causes ___

A

Social withdrawal

Hallucinations

90
Q

Serotonergic neurons are located where im RF

A

All brainstem levels in raphe

91
Q

Nucleus raphe Magnus works with ___ ___

A

Pain modulation

92
Q

Locus ceruleus makes ___

A

Norepinephrine

93
Q

The 4 components to the V nerve are the

A

Mesencephalic nucleus
Main sensory nucleus
Spinal nucleus
Motor nucleus

94
Q

VII receives Afferent fibers from the ___ ___ and ___ ___ of the taste buds, parts of ___ ___ and ___ ___

Sends efferent fibers to control ___ and ___ glands, ___ and ___ glands and ___ glands

Controls muscles of ___ ___ and the ___

A

Outer ear
Anterior 2/3
Nasal cavity
Soft palate

Submandibular
Sublingual
Nasal and palatine

Lacrimal glands

Facial expression
Stapedius

95
Q

VII motor innervates the ___ ___ bilaterally, but the ___ ___ is innervated contralaterally

A

Upper face

Lower face

96
Q

VII Afferent follow what pathway

A

Same as spinal trigeminal

97
Q

The solitary tract deals with ___ sensory from ___ ___

A

Visceral sensory

Taste buds

98
Q

Trigeminal neuralgia can be caused by

A

Trigeminal compression by vessel or tumor

99
Q

Corneal blink reflex: afferent is from ___ and efferent is from ___

A

Vi to SpV

VII

100
Q

Afferent limb of jaw jerk ___ ___

Efferent limb ___ ___

A

Mesencephalic V

V motor

101
Q

Nervus intermedius splits into the ___ ___ nerve and the ___ ___ nerve

A

Great petrosal

Chords typani

102
Q

How are the taste buds innervated

A

VII - anterior 2/3 of tongue (CT), soft palate (GP) both go to GG then to solitary tract

IX - posterior 1/3 of tongue through inferior ganglion of IX to solitary tract

X - pharynx and epiglottis through inferior ganglion of X to solitary tract

103
Q

Pacinian corpuscles detect

A

Vibration

104
Q

Meissner corpuscles detect

A

Discriminative touch

105
Q

Ruffini endings detect

A

Pressure

106
Q

Merkel endings detect

A

Fine two point discrimination

107
Q

DCML path detects ___ ___ ___ and ___ ___

A

Two point discrimination

Conscious proprioception

108
Q

STT / ALP conveys what

A

Pain and temperature

109
Q

The three pathways that go to the cerebellum are the

A

Spinocerebellar tract
Cuneocerebellar tract
Anterior spinocerebellar tract

110
Q

The PSCT conveys what

A

Proprioceptive info

Ipsilateral leg proprioception

111
Q

The cuneocerebellar tract conveys

A

Arm proprioception

112
Q

The ASCT conveys

A

Attempted movement

113
Q

The first Pharyngeal arch cartilage forms which 7 bones and 2 ligaments

A
Maxillary (inc. inf. Nasal concha)
Zygomatic
Vomer
Mandible
Squamous part of temporal
Malleus
Incus

Ant. Ligament of malleus
Sphenomandibular ligament

114
Q

2nd arch forms which 3 bones and which ligament

A

Stapes
Styloid process
Lesser Cornu of hyoid

Stylohyoid ligament

115
Q

The 3rd arch forms which two bones

A

Greater Cornu of hyoid

Body of hyoid

116
Q

4th and 6th arch forms which skeletal elements

A

Thyroid cartilage

Cricoid cartilage

117
Q

1st arch muscles

A

Mastication
Mylohyoid
Ant. Belly of digastric
Tiny tensors

118
Q

2nd arch muscles

A

Facial expression
Stapedius
Posterior belly of digastric
Stylohyoid

119
Q

3rd arch muscles

A

Stylopharyngeus

120
Q

4th/6th arch muscles

A

Pharyngeal constrictor
Levator veli palatini
Cricothyroid
Muscles of larynx

121
Q

Pouch 1 derivatives

A

Tympanic cavity

Eustachian tube

122
Q

Pouch 2 derivatives

A

Palatine tonsil

123
Q

Pouch 3 derivatives

A

Inferior parathyroid gland

Thymus

124
Q

Pouch 4 derivatives

A

Superior parathyroid glands

Ultimopharyngeal body

125
Q

2-4 phar. Grooves/clefts become what

A

Cervical sinus and possibly cervical vesicle

126
Q

Thyroid gland is connected to what

A

Foramen cecum of tongue

127
Q

Difference between cervical cyst and thyroglossal duct cyst

A

Cervical is lateral, thyroglossal is medial

128
Q

What forms the posterior 1/3 of the tongue

A

Hypopharyngeal eminence overgrown copula

129
Q

___ ___ separates the posterior 1/3 from anterior 2/3 of the tongue

A

Terminal sulcus

130
Q

Extrafusal vs intrafusal muscle fibers

A

Extrafusal do work

Intrafusal do maintenance

131
Q

Spastic paralysis is a result of ___ injury

A

UMN

132
Q

Flexor motor neurons are more ___ and extensors are more

A

Posterior

Anterior

133
Q

How to remember type 1 muscle fiber

A

One slow fat red ox

134
Q

___ ___ and ___ control motor movements

A

Basal ganglia

Cerebellum

135
Q

The three most important and three less important descending motor pathways

A

Corticospinal
Corticobulbar
Corticopontine

Rubrospinal
Reticulospinal
Vestibulospinal

136
Q

Corticospinal tract originates in what 5 places

A
Primary motor area (precentral gyrus)
Somatic sensory area (post central)
Premotor area (lateral of cerebrum)
Supplementary motor (medial of cerebrum)
Superior parietal
137
Q

Premotor area does what

A

Plans movement
Controls proximal and axial muscles
Empathetic facial movements

138
Q

Location of premotor area vs supplemental motor area

A

Premotor is lateral and the supplemental is medial

139
Q

Supplemental motor area does what

A

Plans movements while thinking (pitcher planning out game)

140
Q

What influence on motor function does the parietal lobe have

A

Directs motor patterns in response to sensory input

141
Q

T/F all movements are dependent on CST

A

False. After a time you can move again but lose fine finger movement

142
Q

Where does the CST decussate

A

Spinomedullary junction

143
Q

Does all the CST cross

A

80% do

144
Q

Corticospinal tract in brainstem

A

Midbrain - middle third of cerebral peduncle
Pons - right in the anteromedial section
Medulla - pyramids

145
Q

Rubrospinal tract does what

A

Controls shoulder and proximal arm muscles

146
Q

Reticulospinal tract does what

A

Control of axial musculature - walking

147
Q

Vestibulospinal tract does what

A

Controls axial muscles - balance

148
Q

Tectospinal tract does wha

A

Head turning reflexes to visual stimuli

149
Q

Corticobulbar pathway includes which cranial nerves

A

V, VII, X (nucleus ambiguus), XI, XII

150
Q

Lifespan of an olfactory receptor

A

1-2 months

151
Q

Lateral vs medial olfactory Syria

A

Lateral is most significant

Medial is emotional response to smell

152
Q

T/F olfactory is ipsilateral

A

True

153
Q

IV controls which eye muscle

A

Superior oblique

154
Q

VI controls which eye muscle

A

Lateral rectus

155
Q

CN III does what

A

Controls eye muscles except S Oblique and lateral rectus

Controls sphincter papillae muscle

156
Q

III is visible at what brainstem level

A

Rostral midbrain

157
Q

IV is visible at what level

A

Caudal midbrain

158
Q

VI is visible at what brainstem level

A

Caudal pons

159
Q

MLF does what

A

Coordinates eye muscles

160
Q

XII nucleus is visible at what level

A

Rostral medulla

161
Q

IX can be seen on what level

A

Rostral medulla

162
Q

Tongue thrust afferent/efferent limb

A

Afferent is CN V or IX

Efferent is XII

163
Q

Gag reflex afferent and efferent

A

Afferent IX

Efferent X

164
Q

CSF flows from the lateral and third ventricles through the ___ ___ to the ___ ___ then out the ___ and ___ ___ down the brainstem and spinal cord, around the brain surface into the ___ ___ ___

A

Cerebral aqueduct
Fourth ventricle
Lateral and median apertures
Superior sagittal sinus

165
Q

Optic tract fibers end where

A

Lateral geniculate nucleus

166
Q

From the LGN where and how do optic signals travel

A

Through optic radiations to calcarine sulcus