Neuro drugs Flashcards

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1
Q

Levodopa

A

Increase dopamine

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2
Q

Co careldopa

A

Added decarboxylase inhibitor to decrease peripheral Dopa breakdown. Decreases dose requirements and therefore side effects.

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3
Q

Pramipexole, ropinirole

A

D receptor agonist

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4
Q

Rasagiline, selegiline

A

MAOI, enhance dopamine by decreasing breakdown, smooths out motor issues

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5
Q

Entacapone

A

COMT inhibitor, decrease peripheral breakdown of L Dopa- prolongs response to L dopa

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6
Q

Procyclidine

A

Anticholinergic- Ach has antagonistic effect on dopamine and therefore by decreasing Ach it increases dopamine effect.

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7
Q

Amantidine

A

NMDA receptor inhibitor

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8
Q

Pyridostigmine

A

Acetylcholinesterase inhibitor, enhance neuromuscular transmission by decreasing breakdown of ACh at NMJ

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9
Q

S/E L dopa

A

Decrease efficacy as decrease in receptors. Freezing, wearing off

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10
Q

Dopamine agonist S/E

A

Impulse disorder

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11
Q

Anticholinerigc

A

Drowsy, confused, does not treat bradykinesia

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12
Q

ACh esterase inhibitor

A

SSLUDGE

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