Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > Neoplasia VI > Flashcards

Neoplasia VI Flashcards

1
Q

What gene product is associated with BRCA1?

A

DNA repair protein (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What gene product is associated with BRCA2?

A

DNA repair protein (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What gene product is associated with BRAF?

A

B-raf (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What gene product is associated with NF1?

A

RAS GTPase activating protein (RAS-GAP) (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What gene product is associated with NF2?

A

Merlin (schwannomin) protein (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What gene product is associated with DPC4?

A

DPC (pneumonic- Deleted in Pancreatic Cancer) (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What gene product is associated with DCC?

A

DCC (pneumonic- Deleted in Colon Cancer) (p.221)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is PSA used to follow?

A

Prostate specific antigen; used to follow prostate carcinoma (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In what conditions may PSA be elevated?

A

Prostate carcinoma, BPH, prostatitis (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the role of tumor markers in cancer diagnosis?

A

Should not be used as the primary tool for cancer diagnosis; tumor markers may be used to confirm diagnosis, to monitor for tumor recurrance, and to monitor response to therapy (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the tumor marker ‘prostatic acid phosphatase’ used to detect?

A

Prostate carcinoma (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the tumor marker CarcioEmbryonic Antigen (CEA) used to detect?

A

Very non specific marker- produced by 70% of Colorectal and Pancreatic cancers, but also produced by gastric, breast, and medullary thyroid cancers (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a-fetoprotein used to detect?

A

Hepatocellular carcinomas and nonseminomatous germ cell tumors (e.g. testis, ovary) (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where is a-fetoprotein normally produced?

A

By the fetus (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is b-gCG used to detect?

A

Hydatiform moles and choriocarcinomas; Gestational trophoblastic diseases (p.222)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the tumor marker CA-125 used to detect?

A

Ovarian cancer (p.222)

17
Q

What is the tumor marker S-100 used to detect?

A

Melanoma, neural tumors, schwannomas (p.222)

18
Q

What is Alkaline phosphatase used to detect?

A

Cancer metasteses to bone and liver and Paget’s disease of the bone (p.222)

19
Q

What is bombesin used to detect?

A

Neuroblastoma, lung and gastric cancers (p.222)

20
Q

What is Tartrate Resistant Acid Phosphatase (TRAP) used to detect?

A

Hairy Cell Leukemia, a B cell neoplasm (p.222)

21
Q

What type of neoplasm is Hairy Cell Leukemia?

A

A B cell neoplasm (p.222)

22
Q

What is the tumor marker CA-19-9 used to detect?

A

Pancreatic adenocarcinoma (p.222)

23
Q

What type of cancer is Calcitonin used to detect?

A

Medullary thyroid carcinoma (p.222)

24
Q

What type of microbe is HTLV-1?

A

Oncogenic microbe (p.222)

25
Q

What type of microbe is HBV and HCV?

A

Oncogenic microbes (p.222)

Pathology (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions