Neoplasia V Flashcards by Alyssa Blood | Brainscape

Q

What type of gene is p53?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is BRCA1?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is BRCA2?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is p16?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is BRAF?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is APC?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is WT1?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is NF1?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is NF2?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is DPC4?

A

Tumor supressor Gene (p.221)

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Q

What type of gene is DCC?

A

Tumor supressor Gene (p.221)

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Q

What tumors are associated with Rb?

A

Retinoblastoma, osteosarcoma (p.221)

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Q

What tumors are associated with p53?

A

Most human cancers, Li Fraumeni syndrome (p.221)

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Q

What tumors are associated with BRCA1?

A

Breast and ovarian cancer (p.221)

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Q

What tumors are associated with BRCA2?

A

Breast and ovarian cancer (p.221)

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Q

What tumor is associated with p16?

A

Melanoma (p.221)

Q

What tumor is associated with BRAF?

A

Melanoma (p.221)

Q

What tumor is associated with APC?

A

Colorectal Cancer (associated with FAP) (p.221)

Q

What tumor is associated with WT1?

A

Wilms Tumor (nephroblastoma) (p.221)

Q

What tumor is associated with NF1?

A

Neurofibromatosis type 1 (p.221)

Q

What tumor is associated with NF2?

A

Neurofibromatosis type 2 (p.221)

Q

What tumor is associated with DPC4?

A

Pancreatic cancer (p.221)

Q

What tumor is associated with DCC?

A

Colon cancer (p.221)

Q

What gene products are associated with Rb?

A

Inhibits E2F; blocks G1–> S phase (p.221)

Q

What gene products are associated with p53?

A

Transcription factor for p21, blocks G1–> S phase (p.221)