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Pathology > Neoplasia IV > Flashcards

Neoplasia IV Flashcards

1
Q

What type of gene is ras?

A

Oncogene (p.221)

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2
Q

What type of gene is L-myc?

A

Oncogene (p.221)

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3
Q

What type of gene is N-myc?

A

Oncogene (p.221)

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4
Q

What type of gene is ret?

A

Oncogene (p.221)

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5
Q

What type of gene is c-kit?

A

Oncogene (p.221)

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6
Q

What tumor is associated with abl?

A

CML (p.221)

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7
Q

What tumor is associated with c-myc?

A

Burkitt’s Lymphoma (p.221)

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8
Q

What tumors are associated with bcl-2?

A

Follicular and undifferentiated lymphomas (inhibits apoptosis) (p.221)

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9
Q

What tumors are associated with HER2/neu (c-erbB2)?

A

Breast, ovarian, and gastric carcinomas (p.221)

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10
Q

What tumor is associated with ras?

A

Colon carcinoma (p.221)

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11
Q

What tumor is associated with L-myc?

A

Lung tumor (p.221)

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12
Q

What tumor is associated with N-myc?

A

Neuroblastoma (p.221)

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13
Q

What tumors are associated with ret?

A

Multiple Endocrine Neoplasia (MEN) types 2A and 2B (p.221)

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14
Q

What tumor is associated with c-kit?

A

Gastrointestinal stromal tumor (GIST) (p.221)

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15
Q

What gene product is associated with abl?

A

Tyrosine Kinase (p.221)

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16
Q

What gene product is associated with c-myc?

A

Transcription factor (p.221)

17
Q

What gene product is associated with bcl-2?

A

Anti-apoptotic molecule (p.221)

18
Q

What gene product is associated with HER2/neu (c-erbB2)?

A

Tyrosine Kinase (p.221)

19
Q

What gene product is associated with ras?

A

GTPase (p.221)

20
Q

What gene product is associated with L-myc?

A

Transcription factor (p.221)

21
Q

What gene product is associated with N-myc?

A

Transcription factor (p.221)

22
Q

What gene product is associated with ret?

A

Tyrosine Kinase (p.221)

23
Q

What gene product is associated with c-kit?

A

Cytokine receptor (p.221)

24
Q

What conditions make a tumor suppressor gene malignant?

A

Loss of function causes increased cancer risk. Both alleles must be lost for expression of disease (p.221)

25
Q

What type of gene is Rb?

A

Tumor supressor Gene (p.221)

Pathology (14 decks)

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