Neoplasia III Flashcards

1
Q

What neoplasm is associated with Chronic atrophic gastritis?

A

Gastric adenocarcinoma (p.220)

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2
Q

What neoplasm is associated with Pernicious anemia?

A

Gastric adenocarcinoma (p.220)

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3
Q

What neoplasm is associated with postsurgical gastric remnants?

A

Gastric adenocarcinoma (p.220)

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4
Q

What neoplasms are associated with Tuberous sclerosis?

A

Giant cell astrocytoma, renal angiomyolipoma, cardiac rhabdomyoma (p.220)

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5
Q

What neoplasm is associated with Actinic Keratosis?

A

Squamous cell carcinoma of the skin (p.220)

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6
Q

What neoplasm is associated with Barret’s esophagus?

A

Esophageal adenocarcinoma (p.220)

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7
Q

What neoplasm is associated with Plummer-Vinson syndrome?

A

Squamous cell carcinoma of the esophagus (p.220)

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8
Q

What neoplasm is associated with Cirrhosis?

A

Hepatocellular carcinoma (p.220)

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9
Q

What neoplasm is associated with Ulcerative Colitis?

A

Colonic adenocarcinoma (p.220)

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10
Q

What neoplasms are associated with Paget’s disease of bone?

A

Secondary osteosarcoma and fibrosarcoma (p.220)

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11
Q

What neoplasm is associated with immunodeficiency states?

A

Malignant lymphomas (p.220)

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12
Q

What neoplasms are associated with AIDS?

A

Aggressive malignant lymphomas (non-Hodgkin’s), Karposi’s sarcoma (p.220)

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13
Q

What neoplasm is associated with autoimmune diseases (e.g. Hashimoto’s thyroiditis, mysathenia gravis)?

A

Lymphoma (p.220)

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14
Q

What neoplasm is associated with acanthosis nigricans?

A

Visceral malignancy (stomach, lung, uterus) (p.220)

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15
Q

What neoplasm is associated with dysplastic nevus?

A

Malignant melanoma (p.220)

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16
Q

What neoplasms are associated with radiation exposure?

A

Leukemia, sarcoma, papillary thyroid cancer, breast cancer (p.220)

17
Q

What features characterize tuberous sclerosis?

A

Facial angiofibroma, seizures, mental retardation (p.220)

18
Q

What metabolite is deficient in Plummer-Vinson syndrome?

A

Iron deficiency (p.220)

19
Q

What three conditions most commonly lead to cirrhosis of the liver?

A

Hepatitis B, Hepatitis C, alcoholism (p.220)

20
Q

What are the symptoms of acanthosis nigracans?

A

Hyperpigmentation and epidermal thickening (p.220)

21
Q

What conditions make an oncogene malignant?

A

Gain of function mutations increase cancer risk. Need damage to only one allele (p.221)

22
Q

What type of gene is abl?

A

Oncogene (p.221)

23
Q

What type of gene is c-myc?

A

Oncogene (p.221)

24
Q

What type of gene is bcl-2?

A

Oncogene (p.221)

25
Q

What type of gene is HER2/neu (c-erbB2)?

A

Oncogene (p.221)