Neoplasia II Flashcards

1
Q

Of the TNM stages, what is the most important prognostic factor?

A

Metastases (p.219)

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2
Q

What are benign tumors of the epithelium called?

A

Adenomas, papillomas (p.219)

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3
Q

What are benign tumors of blood vessels called?

A

Hemangiomas (p.219)

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4
Q

What are benign tumors of smooth muscle called?

A

Leiomyomas (p.219)

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5
Q

What are benign tumors of striated muscle called?

A

Rhabdomyomas (p.219)

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6
Q

What are benign tumors of connective tissue called?

A

Fibromas (p.219)

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7
Q

What are benign tumors of bone called?

A

Osteomas (p.219)

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8
Q

What are benign tumors of fat called?

A

Lipomas (p.219)

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9
Q

What seven tissue types are considered mesenchymal tissue?

A

Blood cells, blood vessels, smooth muscle, striated muscle, connective tissue, bone, and fat (p.219)

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10
Q

What are malignant tumors of the epithelium called?

A

Adenocarcinomas, papillary carcinomas (p.219)

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11
Q

What are malignant tumors of blood cells called?

A

Leukemias, lymphomas (p.219)

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12
Q

What are malignant tumors of blood vessels called?

A

Angiosarcomas (p.219)

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13
Q

What are malignant tumors of smooth muscle called?

A

Leiomyosarcomas (p.219)

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14
Q

What are malignant tumors of striated muscle called?

A

Rhabdomyosarcomas (p.219)

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15
Q

What are malignant tumors of connective tissue called?

A

Fibrosarcomas (p.219)

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16
Q

What are malignant tumors of bone called?

A

Osteosarcomas (p.219)

17
Q

What are malignant tumors of fat called?

A

Liposarcomas (p.219)

18
Q

What is implicated by the term ‘carcinoma?

A

Epithelial origin (p.219)

19
Q

What is implicated by the term ‘sarcoma?

A

Mesenchymal origin (p.219)

20
Q

What are the most common morphological differences between benign and malignant tumors?

A

Benign tumors are usually well differentiated, slow growing, well demarcated, and without metastasis; malignant tumors may be poorly differentiated with erratic growth and are usually locally invasive/ diffuse and may metastasize (p.220)

21
Q

What is cachexia?

A

Weight loss, muscle atrophy, and fatigue that occur in chronic disease (e.g. cancer, AIDS, heart disease, TB) (p.220)

22
Q

What inflammatory mediators contribute to cachexia?

A

TNF-a, IFN-y, IL-6 (p.220)

23
Q

What neoplasms are associated with Down Syndrome?

A

ALL, AML (p.220)

24
Q

What neoplasms are associated with Xeroderma Pigmentosum?

A

Melanoma, basal cell carcinoma, and especially squamous cell carcinoma of the skin (p.220)

25
Q

What neoplasms are associated with Albinism?

A

Melanoma, basal cell carcinoma, and especially squamous cell carcinoma of the skin (p.220)