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Pharmacology > Neoplasia > Flashcards

Neoplasia Flashcards

1
Q

Erlotinib

A

Inhibidor de tirosina cinasa de EGFR (primera generacion)

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2
Q

Gefitinib

A

Inhibidor de tirosina cinasa de EGFR (primera generacion)

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3
Q

Afatinib

A

Inhibidor de tirosina cinasa de EGFR (segunda generacion)

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4
Q

Omisertinib

A

Inhibidor de tirosina cinasa de EGFR (tercera generacion)

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5
Q

Cetuximab

A

Inhibidor de anticuerpos de EGFR

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6
Q

Panitumumab

A

Inhibidor de anticuerpos de EGFR

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7
Q

Necitumumab

A

Inhibidor de anticuerpos de EGFR

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8
Q

Trastuzumab

A

Inhibidor de HER2

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9
Q

Pertuzumab

A

Inhibidor de HER2

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10
Q

Lapatinib

A

Inhibidor de molécula pequeña de las tirosinas cinasas de EGFR y HER2

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11
Q

Neratinib

A

Inhibidor irreversible de la proteina tirosina cinasa HER2 y EGFR

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12
Q

Olaratumab

A

Inhibidor de PDGFR (receptor de factor de crecimiento derivado de plaqueta)

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13
Q

Vismodegib

A

Inhibidor de la vía de señalización hedgehog

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14
Q

Sonidegib

A

Inhibidor de la vía de señalización hedgehog

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15
Q

Vemurafenib

A

Inhibidor de BRAF

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16
Q

Dabrafenib

A

Inhibidor de BRAF cinasas

17
Q

Trametinib

A

Inhibidor de MEK

18
Q

Cobimetinib

A

Inhibidor de MEK

19
Q

Ruxolitinib

A

Inhibidor de Jak1 y Jak2

20
Q

Palbociclib

A

Inhibidor de CDK4 y CDK6

21
Q

Ibrutinib

A

Inhibidor de tirosina cinasa de Bruton (BTK)

22
Q

Imatinib

A

Inhibidor de la cinasa BCR-ABL (primera generación)

23
Q

Dasatinib

A

Inhibidor de la cinasa BCR-ABL (segunda generación)

24
Q

Nilotinib

A

Inhibidor de la cinasa BCR-ABL (segunda generación)

25
Q

Bosutinib

A

Inhibidor de la cinasa BCR-ABL (segunda generación)

26
Q

Ponatinib

A

Inhibidor de la cinasa BCR-ABL (tercera generación)

27
Q

Crizotinib

A

Inhibidor receptores tirosina cinasa que incluyen HGFR/cMET, ALK y ROS1.

28
Q

Alectinib

A

Inhibidor de actividad de ALK cinasa

29
Q

Ceritinib

A

Inhibidor ALK cinasa

30
Q

Idelalisib

A

Inhibidor isoforma PI3Kδ

31
Q

Rapamicinas

A

Inhiben un complejo enzimático, mTORC1 que ocupa

una posición posterior en la vía PI3K

32
Q

Bevacizumab

A

Anticuerpo que se une a VEGF

33
Q

Ramucirumab

A

Anticuerpo que se une a VEGFR2

34
Q

Aflibercept

A

Inhibidor de VEGF adhiriendo a estos

35
Q

Sunitinib

A

Inhibidor de cinasas de VEGFR2

36
Q

Sorafenib

A

Inhibidor de cinasas de VEGFR2

37
Q

Pazopanib

A

Inhibidor de la cinasa de VEGFR-1, -2 y -3

Pharmacology (7 decks)

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