nefritis lupica Flashcards

1
Q

FR

A

jovenes hispanos
3-6 meses post dx
hombres + frec + grave
raza negra **

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2
Q

cuantos glomerulos se necesitan

A

> 10 glomerulos

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3
Q

casa llena

A

IgG
IgA
IgM
C19
C4
C3

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4
Q

sx nefritico

A

proteinuria >3.5g
HTA
oliguria

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5
Q

SX nefrotico

A

proteinuria <3.5
hematuria - cilindros
edema

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6
Q

escrutinio

A

poliuria (mucho) + nicturia(noche) + bromuria (espumosa)

edema extremidades, HTA; hemtauria, proteinuria

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7
Q

daño glomerular

A

proteinuria
N: <150mg
** recoleccion de orina en 24 hrs

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8
Q

biopsia renal contraindicacion

A

tamaño renal <75% del normal

dm, amiloidosis, niños con corticoesteroides

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9
Q

clasificacion nefritis lupica

A

6

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9
Q

I - minima mesangial

A

depositos inmunes mesangial x inmuoflorescencia

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10
Q

II - mesangial proliferativa

A

hipercelularidad mesangial proliferativa + depositos de complejo inmune

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10
Q

III - focal

A

complejo en endotelio <50% de glomerulos dañados

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11
Q

IV - difusa

todo llenos de complejos (se ve verde todo)

A

complejo en endotelio >50% de glomerulos dañados

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12
Q

V - membranosa

A

complejos en subendotelio (podocito)
>proteinuria caracteristico

tx: para proteinuria, rangos nefroticos 3y4
N: >2.5

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13
Q

VI - esclerosis avanzada

A

> 90% de glomerulos globalmente esclerosados

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14
Q

tratamiento inicial

A

ciclofosfamida o acido fenolitico

15
Q

todo px con lupus se agrega segun la complicacion

A

hidroxicloroquina o cloroquina

16
Q

prevencion en el embarazo

A

hidroxicloroquina

17
Q

III y IV tx

A

hidroxicloroquina + ciclofosfamida + glucocorticoide / ac fenolico

18
Q

glucocorticoide

A

manifestaciones several o exacervacion

19
Q
A