Musculoskeletal Disorders Flashcards
what are w/in these categories
osteoporosis
paget’s disease
osteoporosis
primary (type I and II)
secondary
goes with kyphosis
osteoporosis primary
most common
follows menopause
type 1 and 2
osteoporosis type 1
post menopausal
estrogen deficient
osteoporosis type 2
age
senile
osteoporosis secondary
associated with meds/steroids, other conditions, disease
ex: type 1 diabetes, hyper parathyroid, hyper/hypothyroid
pharmacology for osteoporosis
SERMs
Bisphosphates
Zoledronic acid
PT osteoporosis
fall/fracture prevention
WB and balance (increases bone density)
avoid PT osteoporosis
high impact
plyometrics
flexion, extension, rotation of vertebral column
paget’s disease
aka osteoitis deformans
abnormal bone remodeling with increase bone resorption and excessive, unorganized new bone formation caused by activated osteoclasts
paget’s disease, 2 stages
initial osteoclastic stage
osteoblastic sclerotic phase
initial osteoclastic stage
abnormal clasts multiply/reabsorb bone quickly
osteoblasts sclerotic phase
formation of heavily calcified but weak bone
bones enlarge leading to pain or deformities
clinical manifestations paget’s disease
hypercalcemia
bowling of LE
kyphosis
CN VIII nerve compression
paget’s disease treatment goal
normalize activity of disease for prolonged periods
1st inhibitor of bone resorption