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Teresa_first aid 2015 pg 429-433 > MSK pg 429-433 first aid 2015 > Flashcards

MSK pg 429-433 first aid 2015 Flashcards

1
Q

MCP spared

a. osteoarthris
b. RA

A

osteoarthritis

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2
Q

RA which joint spared

A

DIP

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3
Q

pain improved with rest OA or RA

A

OA

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4
Q

TNF alpha inhibitors for RA

List 3

A

etanercept (Enbrel), adalimumab (Humira), infliximab (Remicade), and certolizumab pegol (Cimzia)

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5
Q

what type of glucocorticoids would you give to osteoarthritis?

A

intra-articular

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6
Q

list two DMARDS for RA

A

Methotrexate

Sulfasalzine

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7
Q

RA association which HLA

A

HLA-DR4

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8
Q

what type of hypersensitivity is RA

A

Type III and IV

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9
Q

Heberden nodes in OA

A

He dips

DIP

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10
Q

Bouchard nodes in OA

A

Baby pip

PIP

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11
Q

Pathology of rheumatoid nodules

A

fibrinoid necrosis

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12
Q

Specific marker for RA

A

anti-cyclic citrullinated peptide antibody

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13
Q

what is RF

A

IgM antibody against Fc portion of IgG

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14
Q

antibodies of sjogren

A

SSA, SSB

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15
Q

what are SS-A and SS-B

A

ribonucleoproteins

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16
Q

Patient with Sjogren suddenly have unilateral enlargement of parotid gland

A

B cell lymphoma (MALT lymphoma)

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17
Q

Patient with acute onset monoarthritis, episodic pain

A

gout

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18
Q

what crystals

  1. gout
  2. pseudogout
A

gout: monosodium urate
pseudogout: calcium pyrophoshate (rhomboid)

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19
Q

what type of joints do pseudogout affect

A

large joint

knee

20
Q

what type of diuretics can cause gout

A 
Thiazide
HyperGLUC
hyperGlycemia,
hyperLipidemia, hyperUricemia,
hyperCalcemia.
21
Q

glycogen storage disease that cause gout

A

von gierke

22
Q

negative birefringent what color

A 
yellow parallel (BLUE parallel in pseudo)
blue perpendicular
23
Q

diseases associated with pseudogout

A

hemachromatosis
hyperparathyroid
osteoarthristis

24
Q

infectious arthrtis in sexually active

A

N. gonorrhoeae

25
Q

IA in older kids and adults

A

S. aureus

26
Q

Gonococal arthrtis presentation

A 
migratory arthritis with asymmetric pattern
STD
synovitis
tenosynovitis
dermatitis
27
Q

Seronegative spondyloarthropathies what HLA

A

HLA-B27 (MHCI)

28
Q

sausage fingers

pencil in a cup

A

psoriatic arthritis

29
Q

Bamboo spine

A

ankylosing spondylitis

30
Q

see Aortic Regurg in which type of Seronegative arthritis

A

Ankylosing spondylitis

31
Q

Can’t see, can’t pee, can’t bend my knee

A

Reactive arthritis reiter

32
Q

cause of reactive arthritis

A

Post GI: shigella, salmonella, Yersinia, Campylo

Chlymadia

33
Q

Circinate balanitis

A

annular dermatitis of glan penis

seen in reiter

34
Q

keratoderma blennorrhagicum

A

hyperkeratotic vesicles in palms and soles

reiter

35
Q

SLE die with what type of kidney disease

A

nephritic DPGN

36
Q

most sensitive SLE

A

ANA

37
Q

most specific

A

dsDNA, anti-smith

38
Q

what is anti-Smith antibodies

A

Anti-snRNPs for splicing

39
Q

drug induced SLE what antibodies

A

anti-histone

40
Q

cause of drug-induced SLE

A

Hydralazine
procanamide
INH

41
Q

SLE patient given hydroxychloroquine. what do you have to monitor

A

retinal exam

42
Q

antibodies in antiphospholipid syndrome

A

lupus anticog
anticardiolipin
anti-B2 glycoprotein

43
Q

false positive VDRL

A 
Viral infection (eg, EBV, hepatitis)
Drugs (IV)
Rheumatic fever
Lupus and leprosy.
Pregnancy
44
Q

lupus anticog produce paradoxical prolongation of PT or aPTT

A

PTT

45
Q

List the joint findings in osteoarthritis (6)

A
  1. Osteophytes (bone spurs)
  2. joint space narrowing
  3. subchondral sclerosis and cysts
  4. eburnation (polished ivory like appearance of bone)
  5. Heberden nodes
  6. Bouchard nodes

Synovial fluid non-inflammatory (WBC

46
Q

this marker in SLE indicate poor prognosis

A

anti-dsDNA

Teresa_first aid 2015 pg 429-433 (1 decks)

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