Mosby's Micro/Path Practice Exam

Question 1

1. all are associated w chronic inflammation except

macrophages
neutrophils
T lymphocytes
B lymphocytes
Plasma Cells

Answer 1

neutrophils

neutrophils are in acute inflammation

Question 2

dust cells can be found in the

brain 
heart
lungs 
liver 
spleen

Answer 2

heart-failure cells and dust cells are macrophages in the lungs
they are part of the reticuloendothelial system

in brain called microglia
in liver called Kupffer cells
in spleen called spleenocytes
in CT called histocytes
in kidneys calles mesangial

Question 3

which of the following mediators aid in the killing of intracellular bacteria

a. histamine
b. interleukin-2
c. catalase
d. IgG
e. lysozyme

Answer 3

intercellular, means “between cells”.
intracellular means “inside the cell”

lysozyme

bacteria that are phagocytized by macrophages are kept in membrane bound vacuoles called phagosomes. a phagasome will fuse with a lysosome which contains many degradative enzymes including lysozymes

Question 4

the class of antibodies that plays an important role in type I hypersensitivity reaction is

Answer 4

IgE = class I. although IgE is the least prevalent Ig (GAMDE). it is usually caused prior sensitization and accumulation in IgE

IgG and IgM = class II
IgG - class III
no antibody class IV

Question 5

DiGeorge’s syndrome is characterized by deficiency of

Answer 5

T lymphocytes.

it is due to the failure of the 3rd and 4th pharyngeal (brachial) pouches forming = lack of thymus and parathyroid

Question 6

Which of the following is the most common cause of subacute endocarditis:

staph aureus
staph epidermidis
strep viridans 
strep pyogenes
strep pneumoniae

Answer 6

strep viridans = most common cause of subacute endocarditis

strep aureus =most common cause of acute endocarditis