Molecules Flashcards

1
Q

p53

A

A tumor supressor, and DNA repair-er

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2
Q

p21

A

tumor suppressor

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3
Q

MDM2

A

binds p53 and degrades it

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4
Q

CDKN2A

A

tumor suppressor

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5
Q

APC

A

tumour suppressor

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6
Q

TBF-B

A

a tumour suppressor, and stops proliferation

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7
Q

MYC

A

growth promoter

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8
Q

PTEN

A

tumor supressor of PI3K/AKT pathway

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9
Q

NF1

A

tumour suppressor of Ras

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10
Q

WT1

A

tumour suppressor

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11
Q

VHL

A

tumour suppressor, and degrades HIF

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12
Q

HIF

A

promotes angiogenesis in hypoxic cells

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13
Q

PD1

A

inhibits T cell activation

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14
Q

myostatin

A

increases protein degradation

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