MOD 9.1 - Neoplasia 2 Flashcards
1
Q
What is metastasis?
A
The development of secondary malignant growths at a site distant from the primary site of cancer
2
Q
How can metastasis travel to other sites?
A
- Through blood
- Through lymph
- Grow directly into the surrounding tissue
3
Q
What is invasion of a metastasis?
A
- Cells pass through the basement membrane and extra cellular matrix
4
Q
What is tumour burden?
A
- The number of cancer cells, size of a tumour or amount of cancer in the body
- Invasion + metastasis = ↑ tumour burden
5
Q
Why does tumour burden not increase with benign tumours?
A
They don’t metastasise
6
Q
What is tumour dormancy?
A
Tumour cells are quiescent and therefore do not divide. They wait for an appropriate stimulus for proliferation
