MOD 1 Flashcards
combine to form cells, the basic structural and functional units of an
organism.
Molecules
are the smallest living units in the human body.
cells
are groups of cells -
perform a particular function
Tissues
- Fluid-mosaic lipid bilayer (phospholipids, cholesterol, and glycolipids) studded w/
proteins; surrounds cytoplasm.
PLASMA MEMBRANE
PLASMA MEMBRANE FX
o Protects
o contact w other cells
o Contains channels, transporters, receptors, enzymes, cell-identity markers, and
linker proteins
o Mediates entry and exit of subs
CYTOPLASM
Consists all cellular contents between the plasma membrane and the nucleus
two components OF CYTOPLASM:
CYTOSOL (INTRACELLULAR FLUID) = 55% of total cell volume ; cell metabolic rxn occur
ORGANELLES = little organs; surrounded by cytosol
CYTOSKELETON
Network of 3 types of protein filaments: microfilaments,
intermediate filaments, and microtubules
- Maintain shape & gen cell orgz ; resp for cell movements.
CELL PARTS
PLASMA MEMB
CYTOPLASM
NUCLEUS
CENTROSOME
pair of centrioles plus pericentriolar material
- pericentriolar material (tubulins =
growth of mitotic spindle and microtubule formation)
cell mobility w 20 microtubules
and a basal body.
CILIA AND FLAGELLA
CILIA VS FLAGELLA
Cilia = move fluids over a cell’s surface;
flagella = move entire
cell.
Responsible for protein synthesis
RNA & PROTEINS
RIBOSOME
Membranous network of flattened sacs or tubules.
ENDOPLASMIC RETICULUM (ER)
Covered by ribosomes
attached to: nuclear
envelope
o Synthesizes glycoproteins and phospholipids
(transferred to cell orgs, inserted into the
plasma membrane, or secreted during exocytosis.)
Rough ER
Synthesizes fatty acids and steroids;
inactivates/ detox drugs;
removes the phosphate group from
glucose-6-phosphate;
stores and releases calcium
ions in muscle cells
Smooth ER
3–20 flattened membranous sacs called cisternae;
GOLGI COMPLEX
PARTS OF GOLGI C
Entry (cis) face = accepts proteins from rough ER;
medial cisternae = form glycoproteins, glycolipids, and lipoproteins;
exit (trans) face = modifies mols further, then sorts and
packages them for transport to their destinations
- formed from Golgi complex; contains digestive
enzymes. - Fuses & digests endosomes contents , pinocytic
vesicles, and phagosomes
transports final products of
digestion into cytosol; digests worn-out organelles
(autophagy), entire cells (autolysis), and extracellular materials.
LYSOSOME
- Vesicle containing oxidases (oxidative enzymes) and catalase
(decomposes hydrogen peroxide); - Oxidizes amino acids and fatty acids;
detox harmful
substances (alcohol)
produces hydrogen peroxide.
PEROXISOME
- Tiny barrel-shaped structure
contains: proteases
(proteolytic enzymes)
- Degrades unneeded, damaged, or faulty proteins
(by cutting into small peptides.)
PROTEASOME
- “Powerhouse of the cell”
- Consists : outer and an inner mitochondrial membrane
cristae, and matrix; - Site of aerobic cellular respiration rxn (produce most ATP)
MITOCHONDRION
- houses cell’s DNA
NUCLEUS
hereditary units - control
most aspects of cellular structure and function
genes
2 TYPES OF CELL DIVISION
somatic cell division = BODY ; TISSUE GROWTH (DEAD CELLS)
reproductive cell division = produce : GERM CELL / GAMETE ; MEIOSIS (chromosome# reducedbyhalf)
mitos
=thread
BODY CELL NUCLEAR DIVISION
mitosis
cytoplasmic division
cytokinesis
RESULT OF soma div
2 DIPLOID
23 pairs
46 chromosomes
Period
between cell
divisions;
chromosomes
not visible
under light
microscope
Interphase
Parent cell
produces
identical cells
with identical
chromosomes;
chromosomes
visible under
light
microscope.
Mitotic
SOMATIC DIV CYCLE
I. INTERPHASE
- G1
- S
- S2
II. MITOTIC PHASE
- MITOSIS - PMAT
- CYTOKINESIS
GERM DIV CYCLE
MEIOSIS I - P1M1A1T1
MEIOSIS II - P2M2A2T2
RESULT OF GERM CELL DIV
4 HAPLOID (23 CHROMOSOME EACH)
Cells that remain in the G1 phase for
a very long time, and possibly never
divide again
G0 phase
- Metabolically active cell duplicates
organelles and cytosolic components - Replication of chromosomes begins.
G1 phase
- Replication of DNA and centrosomes.
S phase
- Cell growth, enzyme and protein
synthesis continue - Replication of centrosomes complete.
G2 phase
- Nuclear
division;
distribution of
two sets of
chromosomes
into separate
nuclei.
Mitosis
Chromatin fibers condense into paired
chromatids;
nucleolus and nuclear
envelope disappear;
each centrosome
moves to an opposite pole of the cell.
Prophase
- Centromeres of chromatid pairs line
up at metaphase plate.
Metaphase
- Centromeres split
- Identical sets of chromosomes move
to opposite poles of cell.
Anaphase
- Nuclear envelopes and nucleoli
reappear;
chromosomes resume
chromatin form;
mitotic spindle
disappears.
Telophase
Cytoplasmic division;
contractile ring
forms cleavage furrow around center
of cell, dividing cytoplasm into
separate and equal portions.
Cytokinesis
mei-
-osis
= lessening
= condition of
two sister chromatids of each pair of homologous
chromosomes pair off,
synapsis;
resulting 4 chromatids form a structure called
tetrad
exchange bn (genetically different) chromatids
crossing-over
- Covers body surfaces and lines hollow
organs, body cavities, and ducts. - forms glands.
- never covered by another tissue= free surface
has its own nerve supply, -but is avascular
epithelium
Exchange of substances
between epithelium and connective tissue
occurs by
diffusion
(EPITHELIUM) blood vessels that bring in nutrients & remove wastes are located in the
adjacent connective tissue
2 TYPES OF EPITHELIAL TISSUE
Covering and lining epithelium
Glandular epithelium