Mitosis And Cell Cycle Flashcards

1
Q

What happens during S phase?

A

Cell replicates DNA ready for mitosis

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2
Q

What is G1 phase? What is G2 phase?

A

Cell grows, in G2 proteins needed for mitosis made.

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3
Q

What is the order of mitosis?

A

Interphase

Prophase, metaphase, anaphase, telophase

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4
Q

What happens in prophase?

A

Chromosomes condense and get shorter
Centrioles move to opposite poles
Spindle fibres form
Nuclear envelope breaks open and chromosomes free

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5
Q

What happens in metaphase?

A

Chromosomes line up along the equator

Attached to spindle fibres by centromere

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6
Q

What is anaphase?

A

Centromeres divide and separate sister chromatids

Spindles contract and pull chromatids to opposite poles

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7
Q

What is telophase?

A

Chromatids uncoil. Long thin chromosomes again
Two nuclear envelopes reform
Cytoplasm divides

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8
Q

What is interphase?

A

Cell carries out normal functions and prepares to divide. DNA unravels and replicates. ATP content is increased

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9
Q

What is mitotic index?

A

The percent of cells with visible chromosomes

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10
Q

How is cancer caused?

A

A mutation in a gene, divides out of control into a tumour.

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11
Q

How can cancer be treated?

A

Disrupt cell cycle - also kills healthy cells. Chemo - Prevent enzyme synthesis, no DNA replication
Radiation - damage DNA, does

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