Mitochondria and AD

Question 1

What are some core functions of mitochondria in the brain?

Answer 1

1) ATP production
2) Calcium regulation
3) Cell death

Question 2

What neurological diseases are associated with mitochondrial pathology?

Answer 2

1) AD
2) PD
3) HD
4) ALS
5) Epilepsy
6) Autism
etc.

Question 3

What are the issues in mitochondrial pathologies?

Answer 3

1) Respiratory chain dysfunction
2) Abnormal localisation and movement
3) Aberrant calcium handling
4) More sensitive permeability transition