Miscarriage Flashcards

1
Q

What is the term for a loss preior to implantation?

A

Pre-implantation pregnancy loss

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2
Q

What is a biochemical pregnancy?

A

Peri-implantational loss: positive pregnancy test but no gestational sac anywhere

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3
Q

What are the weeks that a pregnancy is considered a miscarriage?

A

5-19

week 20+ is a stillbirth

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4
Q

What is an embryonic loss?

A

5-10 weeks gestational age

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5
Q

What is an early fetal loss?

A

10-16 weeks

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6
Q

What is a late fetal loss?

A

16-20 weeks

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7
Q

What is an early pregnancy loss?

A

before 10 weeks

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8
Q

What is a threatened miscarriage?

A

Pregnancy bleeding but no tissue passed- possible viable pregnancy

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9
Q

What is a missed miscarriage?

A

pregnancy not viable via US or HCG but little to no bleeding yet

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10
Q

What is a complete miscarriage?

A

Everything has happened

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11
Q

At what week is miscarriage most likely?

A

Week 8

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12
Q

What is the overall risk of miscarriage?

A

12-15%

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13
Q

What is defined as a recurrent miscarriage?

A

Two or more

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14
Q

What are the main known risk factors for miscarriage?

A

Genetic abnormality- chromosomal (AGE)
Previous history of miscarriage

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15
Q

What proportion of miscarriages are most likely preventable based on our current knowledge?

A

Less than 30%

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16
Q

In attempting to achieve pregnancy what is the TSH level at which thyroid replacement will happen?

A

Thyroid replacement for TSH > 2.5

17
Q

What was the PROMISE study and what did it show?

A

Vaginal progesterone for recurrent miscarriage

Showed a 3% increase of live births with progesterone treatment

18
Q

What is the PRISM study and what did it show?

A

Vaginal progesterone for threatened miscarriage

3% increase in live births with progesterone

19
Q

A couple is trying to get pregnant after using the Creighton method for 7 cycles following three miscarriages. At their 8 week ultrasound there was a fetal heartbeat and embryo visible. At 8 weeks 6 days the woman experienced bleeding. She called her physician and asked for an intervention which could increase the probability of the continuation of a successful pregnancy.

What intervention could be offered to this patient that has been shown to increase the live birth rate?

A

progesterone 400mg PV twice daily

20
Q
A