misc Flashcards

1
Q

Patients taking selegiline may test positive for

A

Methamphetamine

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2
Q

Managing Lithium side effects:

A

GI issues: change to longer acting preparation or use lithium citrate syrup

Hypothyroidism: Treat with thyroid hormone

Tremor: treat with propranolol or primidone

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3
Q

Anorexic patient complains of constipation, what med do you give?

A

Do not give a laxative (lactulose, senna, magnesium hydroxide). Give a stool softener (docusate)

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4
Q

Which is a good hypnotic for the elderly

A

Ramelteon

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5
Q

When detoxing an alcoholic who has liver impairment, which is the best medication?

A

Ativan or Oxazepam (they’re easy on the liver)

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6
Q

What does Lithium do to the parathyroid gland?

A

Hyperparathyroidism

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7
Q

What’s the max dose of focalin for kids age 6 to 17

A

20mg

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8
Q

PCP intoxication signs

A

Impulsiveness, unpredictable, psychomotor agitation, aggression, HTN, tachy, ataxia, muscle rigidity, seizures. It’s the only drug that can cause VERTICAL nystagmus, but it can also cause horizontal or rotary nystagmus.

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9
Q

Dissociative (psychogenic) amnesia includes loss of

A

autobiographical memory, sometimes with preserved ability for new learning

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10
Q

What meds can cause agranulocytosis

A

Mirtazapine (and carbamazepine and Clozaril)

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11
Q

Sensitivity and specificity

A

“Sensitivity” has an “n” in it and so does the word “in”

Sensitivity is to rule in a disease (true positive)

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12
Q

Selegiline absolute contraindications

A

Pheochromocytoma and surgery

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13
Q

What is the primary, direct cause of neuron loss in an ischemic stroke

A

Excessive increases in excitatory neurotransmitters

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14
Q

Drugs the autoinduce their own metabolism

A

Carbamazepine, cyclophosphamide, theophylline, ifosfamide, aminoglutethimide

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15
Q

Custody of children cases must be determined by

A

A forensic evaluator

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16
Q

Somatic symptom disorder

A

Somatic symptoms that are distressing and accompanied by excessive thoughts and fears.

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17
Q

These meds should be discontinued before ECT because they can interfere with the effects

A

Lithium, benzos, anticonvulsants, and theophylline

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18
Q

Giving antidepressants in the 3rd trimesters can have what risk for the baby

A

Discontinuation syndrome

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19
Q

Criteria for Alcohol Use Disorder, Severe

A

At least 6 items are present

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20
Q

Carbamazepine is metabolized in the liver by

A

CYP34A

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21
Q

GHB (Xyrem)

A

A schedule III med used for cataplexy in narcolepsy

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22
Q

Yohimbine

A

An alpha agonist that can help men with SSRI induced sexual dysfunction, but also causes anxiety

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23
Q

Fluoxetine increases the drug levels of

A

TCAs, thioridazine, benzos, carbamazepine, phenytoin, warfarin, and bupropion

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24
Q

Sumatriptan

A

Used to treat migraine and cluster headaches. It’s a 5HT1D and 5HT1B agonist

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25
Q

When does someone usually have their first panic attack

A

Out of the blue while doing everyday things

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26
Q

The Maudsley Model is used to treat

A

Anorexia

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27
Q

Folate deficiency can result in

A

Macrocytic anemia

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28
Q

1mg of Xanax = __mg of Ativan

A

2

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29
Q

Antidote of benzo overdose

A

Flumazenil

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30
Q

Zaleplon

A

It’s the only hypnotic that can be taken in the middle of the night without causing significant grogginess in the morning. It has a short half-life, 1 or 2 hours. (“If you buy her a ring at Zales, you’ll have a short married life).

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31
Q

How do you add lamotrigine for a patient who is on valproate

A

Halve the starting dose because valproate doubles the level of lamotrigine

32
Q

For borderlines, the 1st line medication treatment for impulsivity and instability is

A

Lithium

33
Q

Body dysmorphic disorder is often comorbid with

A

Social phobia

34
Q

Best treatment for paranoid personality disorder

A

Individual therapy

35
Q

In what stage do they understand no matter shape the clay is in, it’s still clay

A

Concrete operations

36
Q

What’s an example of a 2nd gen that’s FDA approved for bipolar depression

A

Quetiapine

37
Q

What’s an antidepressant that doesn’t have a lot of drug-drug interactions for older adults

A

Sertraline

38
Q

What are 3 examples of meds you should not give with bupropion because they lower seizure threshold

A

Clozapine, theophylline, clomipramine

39
Q

In illness anxiety disorder, criterion D is

A

The person has excessive health related behaviors

40
Q

The problems linked to Freud’s oral stage

A

Paranoia, schizophrenia, substance abuse

41
Q

Early onset bipolar is less responsive to

A

Lithium

42
Q

Maximum daily dose for divalproex sodium

A

60mg/kg/day

43
Q

Acne is a side effect of

A

Lithium

44
Q

How many symptoms are required for the diagnosis of panic disorder

A

4

45
Q

Nortriptyline and the elderly

A

Even though it’s a TCA, it’s a first line option for elderly people with melancholic depression

46
Q

What’s a complementary therapy that can help with OA and RA pain

A

Acupuncture

47
Q

Anticonvulsant medications that are pregnancy C

A

Gabapentin, pregabalin, lamotrigine

48
Q

What area of the brain does smell

A

Limbic

49
Q

Adult patient, myoclonic jerks, rapid progress toward dementia, akinetic mutism

A

Creutzfeldt-Jakob

50
Q

Agitated patient has vertical nystagmus, rotary nystagmus, and psychotic behavior. What do you do?

A

He’s high on PCP, give benzos for agitation.

51
Q

Carbamazepine causes what electrolyte imbalance

A

Low sodium

52
Q

Carbohydrate deficient transferrin

A

A biomarker for alcohol use

53
Q

Medicare part A covers

A

Inpatient hospital stay, SNF, hospice, home health care

54
Q

Medicare part B covers

A

Clinical research, ambulance, durable medical equipment, limited prescription drugs, psych treatment

55
Q

How long does it usually take before DTs happen

A

2 to 3 days

56
Q

What kind of inhibitor is ketoconazole

A

CYP3A4

57
Q

What is a benefit of Ramelteon

A

It’s a sleep medication that doesn’t carry abuse potential

58
Q

Bupropion can increase levels of

A

Amitriptyline

59
Q

Carbamazepine induces

A

Theophylline

60
Q

Childhood onset fluency disorder means

A

Stuttering

61
Q

Ramelteon mechanism

A

Melatonin 1 and 2 agonist

62
Q

Separation anxiety is normal between ages

A

10 to 18 months

63
Q

The antidote to prevent systemic effects of benzo intoxication is

A

Flumazenil (not flurazepam)

64
Q

Which drug has the best evidence for treating drug-induced psychosis in Parkinson’s patients

A

Clozaril

65
Q

What is the minimum baseline ANC you need to have before starting Clozaril

A

1500

66
Q

What do you give for anticholinergic delirium (anticholinergic overdose)

A

Physostigmine

67
Q

What condition has low CoQ10 levels

A

Parkinsons

68
Q

The most common comorbidities with Fragile X syndrome are

A

ADHD and social anxiety disorder

69
Q

Desvenlafaxine fun facts

A

It’s weakly protein bound and has an earlier onset of action compared to other antidepressants.

70
Q

Topiramate and oral contraceptives

A

Topiramate effects the efficacy, but only at doses of 200mg or more

71
Q

Varenicline mechanism of action

A

Partial agonist at alphabeta and full agonist at alpha7

72
Q

Carbamazepine when breastfeeding?

A

It’s safe

73
Q

Inducers: GPS Cell Phone Ring

A
Griseofulvin
Phenytoin
Smoking
Carbamazepine
Phenobarbital
Rifampin
74
Q

Which exam would you give for a patient over 50 with change in mental status, mood, personality, or behavior

A

MRI

75
Q

Conversion disorder, illness anxiety disorder, and somatic symptom disorder

A

Conversion disorder happens and resolves quickly, and they’re not that upset about. Illness anxiety is when they are fine but worry about being sick. Somatic symptom is when they are sick, but they’re way too worried about it.