Migraine Flashcards
Ergotamine tartrate (Ergomar)
oral, sublingual, rectal; ergotamine tartrate (1mg)/caffeine (100mg)/1-belladona alkaloids (0.125mg)/sodium pentobarbital (30mg) (Ercaf, Wigraine); ergotamine tartare (2mg)/caffeine (10mg) (cafergot suppository)
dihydroergotamine (D.H.E. 45)
dihydroergotamine mesylate nasal spray (Migranol)
Specific 5-HT 1B/1D agonists
sumatriptan (Imitrex) - 1st gen
zolmitriptan (Zomig, Zomig ZMT) - 2nd
Dopamine Antagonists - antiemetics (IV, IM or oral)
Metoclopramide (Reglan)
Prochlorperazine (Compazine)
Chlorpromazine (Thorazine)
Analgesics
Aspirin
Acetaminophen (Tylenol)
Ibuprofen (advil, motrin)
Miscellaneous drugs
Beta-blockers (propranolol, timolol, atenolol, metoprolol, nadolol)
Antidepressants - amtriptyline (Elavil)
Anticonvulsant drugs - valproate (depakote), topiramate (Topamax), gabapentin (neurontin)
Botulinum toxin type A (botox)
Prodrome
less than and equal to 60%; changes in mood (depression, irritability, etc…) &appetite (food cravings) that occur hours to days before the migraine
Aura
Migraine without aura (Common Migraine)
Migraine with aura (Classic Migraine)
less than equal 25% of people with migraine
Migraine head pain
less than or equal to 2 attacks per week; abortive therapy
more than or equal to 3 attacks per week; prophylactic therapy
abortive therapy
to avoid the problem of rebound headaches abortive therapy should be used ~2 times a week
Acetaminophen
efficacious in treating migraine pain and symptoms including photophobia and phonophobia
Sumatriptan (Imitrex)
Triptans are used for the acute treatment of moderate to severe migraines
Triptan symptoms
common w/ Sumatriptan and newer triptans, chest and throat tightness, difficulty breathing, panic/anxiety, paresthesia, feeling of heaviness
Drugs for the acute/abortive treatment of cluster headache
oxygen
ergotamine
sumatriptan
drugs for the acute/abortive treatment of tension headache
otc analgesics
relaxation