Migraine Flashcards
Ergotamine tartrate (Ergomar)
oral, sublingual, rectal; ergotamine tartrate (1mg)/caffeine (100mg)/1-belladona alkaloids (0.125mg)/sodium pentobarbital (30mg) (Ercaf, Wigraine); ergotamine tartare (2mg)/caffeine (10mg) (cafergot suppository)
dihydroergotamine (D.H.E. 45)
dihydroergotamine mesylate nasal spray (Migranol)
Specific 5-HT 1B/1D agonists
sumatriptan (Imitrex) - 1st gen
zolmitriptan (Zomig, Zomig ZMT) - 2nd
Dopamine Antagonists - antiemetics (IV, IM or oral)
Metoclopramide (Reglan)
Prochlorperazine (Compazine)
Chlorpromazine (Thorazine)
Analgesics
Aspirin
Acetaminophen (Tylenol)
Ibuprofen (advil, motrin)
Miscellaneous drugs
Beta-blockers (propranolol, timolol, atenolol, metoprolol, nadolol)
Antidepressants - amtriptyline (Elavil)
Anticonvulsant drugs - valproate (depakote), topiramate (Topamax), gabapentin (neurontin)
Botulinum toxin type A (botox)
Prodrome
less than and equal to 60%; changes in mood (depression, irritability, etc…) &appetite (food cravings) that occur hours to days before the migraine
Aura
Migraine without aura (Common Migraine)
Migraine with aura (Classic Migraine)
less than equal 25% of people with migraine
Migraine head pain
less than or equal to 2 attacks per week; abortive therapy
more than or equal to 3 attacks per week; prophylactic therapy
abortive therapy
to avoid the problem of rebound headaches abortive therapy should be used ~2 times a week
Acetaminophen
efficacious in treating migraine pain and symptoms including photophobia and phonophobia
Sumatriptan (Imitrex)
Triptans are used for the acute treatment of moderate to severe migraines
Triptan symptoms
common w/ Sumatriptan and newer triptans, chest and throat tightness, difficulty breathing, panic/anxiety, paresthesia, feeling of heaviness
Drugs for the acute/abortive treatment of cluster headache
oxygen
ergotamine
sumatriptan
drugs for the acute/abortive treatment of tension headache
otc analgesics
relaxation
drugs for the prophylactic treatment of cluster headache
verapamil
lithium
ergotamine
prednisone
drugs for the prophylactic treatment of tension headache
amitriptyline
botox
migraine in children
Shorter duration of head pain (30 min). 1st step is to eliminate possible food triggered in child's diet. otc analgesics advil, tylenol antiemetic domperidone beta blockers - prophylactic triptans - acute