Midterm 1 - Lecture 2 Flashcards
Name all the organs of digestion
• Mouth • Esophagus • Stomach • Small Intestine • Large Intestine • Accessory Organs ((liver, pancreas, gall bladder & salivary glands)
Fxns of saliva
Digest carbohydrates with salivary amylases
Lubricate (mucous)
Antimicrobial (lysozyme that digests bacterial cell walls)
—Bolus formation—
Fxns of Taste Receptors
- Sweet and salt receptors attract us to carbs and salt
- Bitter receptors repel us from toxins
- Sour receptors repel us from fermented (acidic) food
- Umami receptors attract us to protein
Interactions between salt, bitter & sour receptors:
attracts us to food
Interactions between salt, bitter & sour receptors:
>300mM Na
activates sour & bitter receptors causing aversion
Interactions between salt, bitter & sour receptors:
Inactivate bitter or sour receptors
lose aversion to high salt
Characteristics of Esophagus
secretes water & mucus
movement by peristalsis
Entry to Esophagus controlled by
upper esophageal sphincter
Back flow into esophagus controlled by
cardiac (lower esophageal) sphincter
Fxns of stomach
- Residence time: 2-3 hr
- solubilize and digest food to acid chyme
- Releases acid (HCl, drops pH to 1-2) and proteases
- Acid denatures proteins (inactivates salivary amylase), hydrolyzes carbs, dissolves minerals (e.g. Ca), kills microbes, activates pepsinogen to pepsin
Fxn of parietal cells in stomach
release HCl
Fxn of chief cells in stomach
store then release pepsinogen
Pepsinogen is activated by acid and becomes:
pepsin
Fxn of Surface mucous cells
release mucus: protects stomach lining from acid
and proteases and from inflammation induced by food antigens
Infant Stomach/Digestion
lower acid production