microbio

Question 1

what is C difficile?

Answer 1

gram +Ve anaerobic motile bacillus, spore producing

Question 2

symptoms/signs of C difficile?

Answer 2

• diarrhoea
• loss of appetite
• temperature
• nausea
• Increased WCC

Question 3

treatment for moderate C difficile?

Answer 3

metronidazole

Question 4

treatment for severe C difficile?

Answer 4

vancomycin

Question 5

how to deal with C difficile in general?

Answer 5

SIGHT
S- suspect
I- isolate within 2 hours
G- gloves and aprons
H- hand wash with soap
T- test immediately

Question 6

investigations to detect C difficile?

Answer 6

immunoassay for glutamate dehydrogenase

Question 7

what is giardisasis?

Answer 7

-flagellated protozoa giardia lambila infection

Question 8

what are risk factors of getting giardisasis?

Answer 8

• contaminated water supply

- swimming in ponds

Question 9

what are the symptoms of giardisasis?

Answer 9

• acute diarrhoea > a week
• abdominal cramps
• bloating
• malabsorption (steatorrhea + weight loss)

Question 10

how to test for giardisasis?

Answer 10

3 seperate stool samples for ova and parasites

Question 11

what is tropical sprue?

Answer 11

-malabsorption disease, commonly found in tropical regions

Question 12

what causes tropical sprue?

Answer 12

-the colonisation of the intestine by infectious agent

Question 13

what are the symptoms of tropical sprue?

Answer 13

• sterorrhoea
• diarrhoea
• weight loss
• nausea
• anorexia
• anaemia

Question 14

how is tropical sprue diagnosed?

Answer 14

• diagnosis of exclusion

- endoscopy + biopsy

Question 15

what are complications of tropical sprue?

Answer 15

-folate deficiency and protein malabsorption

Question 16

how is tropical sprue treated?

Answer 16

-tetracycline, folic acid (broad spectrum antibiotics)