Methods of extraction Flashcards
meaning of Macerare
to soak
process in which the properly comminuted drug is permitted to
soak in the menstruum until cellular structure is softened and
penetrated by the menstruum and soluble constituent is dissolved.
Maceration
Maceration is agitate repeatedly over a period usually ranging from ___ to ___ days
2 to 14 days
Where does the word percolation come from
per (through) and colare (to strain)
process where the comminuted drug is extracted by the slow
passage of a suitable solvent through a column of the drug.
Percolation
drawn by the force of gravity as well as the weight of the column of
liquid
Percolation
Percolation is where the _____ drug is extracted by the ____________________
comminuted, slow passage of a suitable solvent through a column of the drug
Percolation on small scale
use of glass percolators
is suited to the complete extraction of drugs
with a minimal expenditure of menstruum.
Cylindrical percolators
Licorice root Fluidextract
Glycyrrhiza Fluidextract
Yerba Santa fluidextract
Eriodictyon Fluidextract
Licorice root Fluidextract use
flavoring agent
Yerba Santa fluidextract use
cathartic
Cascara Sagrada Fluidextract
Rhamnus Purshiana Fluidextract
Fluidextratum Sennae
Senna Fluidextract
official preparation
1. Glycyrrhiza Fluidextract
2. Eriodictyon Fluidextract
3. Cascara Sagrada Fluidextract
4. Aromatic Cascara Sagrada Fluidextract
5. Senna Fluidextract
concentrated preparations of vegetable or animal drugs obtained by the removal of the active constituents of the respective drugs with suitable solvent
Extracts
Characteristics of extracts
syrupy
add solvent system to drug either macerate/percolate
obtain through evaporation
2-6 times more potent than crude drugs
Extracts are made in 3 forms:
Syrupy/semiliquid
Pilular/plastic consistency
Powdered extract
20 ml of solvent system is remained
- removing all or most of the menstruum
syrupy/semiliquid
nearly all solvent (menstruum) has evaporated
pilular/plastic consistency
preferred in compounding a ;oastic dosage form:
ointment/paste/pliable material facilitates compounding
Pilular/plastic consistency
dry extract by removal of all
menstruum
powdered extract
vegetable drug material which are starchy
powdered extract
preferred in compounding of: powders, capsules & tablets
Powdered extract
treatment of rhinitis of the common cold, for sinusitis
NASAL DECONGESTANT SOLUTIONS