Metabolismul lipidic Flashcards

1
Q

Sarurile biliare -alcatuire

A

inel sterolic si o catena laterala de care s epoate lega o taurina sau o glicina

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2
Q

lipaza pancreatica pe ce carboni actioneaza preferential

A

c1 c3

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3
Q

colipaza pancreatica

A

Secretata in raport de 1:1 cu lipaza pancreatica
este secretata suub forma de zimogen , pro-colipaza, activata de tripsina. Ancora lipaza la interfata molecula lipidica - strat apos unde are loc modificarea comformationala a lipazei si expunerea situsurilor active.

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4
Q

Orlistatul = tetrahidrolipstatin

A

-este un medicament utilizat in tratamentul obezitatii, care inhiba lipazele pancreatica si gastrica si scade absorbtia de grasimi

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5
Q

CCK

A

Este produsa de mucoasa jejunuului si ileonului terminal, fiind o hormon peptidic, este produs ca raspuns la prezenta produsilor de digestie partiala a lipidelor si proteinelor . Deternina eliberarea bilei din vezica biliara, eliberarea enzimelor pancreatice.
Inhiba motilitatea gastrica , continutul gastric ajunge astfel mult mai lent in intestinul subtire,

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6
Q

Secretina

A

stimuleaza eliberarea de catre ficat si pancreas a unei solutii apoase bogate in bicarbonat care neutralizeaza aciditatea continutului intestinal pentru a favoriza actiunea enzimelor pancreatice.

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7
Q

Lipide simple

A

AG, colesterol

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8
Q

Lipide complexe

A

Fosfolipidele

Sfingolipidele

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9
Q

A/F Cea mai importanta rezerva energetica a organismului sunt TAG stocati in celule.

A

adevarat!

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10
Q

A/F la ag nesaturati legaturile duble sunt conjugate.

A

FALS. sunt in pozitie malonica, separate mereu de trei atomi de carbon

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11
Q

Acizi grasi essentialia

A

Acidul linoleic- precursor al aicdului arahidonic care este precursor al prostaglandinelor
Acidul alfa-linolenic (w3)

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12
Q

Cei mai importanti membri w6

A

Acidul linoleic
Acidul arahidonic
Acidul gama linolenic

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13
Q

Cei mai importanti membri w3

A

Acidul alfa-linolenic
EPA acidul eicosapentanoic
DHA acidul docosahexaenoic

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14
Q

La ce duce deficienta de acizi grasi esentiali . rara / frecventa

A

Este rara si duce la dermatita exfoliativa, infertilitate precum si tulburari vizuale si neurologice.

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15
Q

tiokinaza de la nivelul membranei mitocondriale externe

A
  • cataliza procesul de transformare a LCF in derivatul sau cu coA
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