Metabolism Lipidic Flashcards

1
Q

Acizii grasi (AG): VN

A

15-25 mg/dl

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2
Q

Trigliceride (TG): VN

A

50-150 mg/dl

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3
Q

Ser cu TG in cantitate mare

A

ser lactescent

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4
Q

TG 160-199 mg/dl

A

dislipidemie de granita cand este asociat cu HDL scazut si colesterol total de granita

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5
Q

TG 200-499 mg/dl

A

hipertrigliceridemie moderata cu risc coronarian moderat

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6
Q

TG >500

A

hipertrigliceridemie severa cu risc coronarian crescut si risc crescut de PANCREATITA ACUTA !!

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7
Q

TG cresc in:

A

HLP primare
HLP secundare
obezitate
alcoolism/ciroza
pancreatita
SN
HTA, IMA
hipotiroidism
DZ
tratament cu estrogeni

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8
Q

TG scad in:

A

hipertiroidism
malnutritie
malabsorbtie
afectiuni hepatice in stadiu final

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9
Q

Colesterolul VN

A

150-220 mg/dl

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10
Q

CT 200-239 mg/dl

A

valori de granita pt riscul dezvoltarii bolii arteriale coronariene

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11
Q

CT >240 mg/dl

A

risc crescut de boala coronariana

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12
Q

CT 240-299 mg/dl

A

hipercolesterolemie moderata

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13
Q

CT >300 mg/dl

A

hipercolesterolemie severa

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14
Q

CT creste in:

A

-dieta bogata in colesterol si grasimi saturate
-HLP primare (hipercolesterolemie familiala/poligenica; IIa si IIb + disbetalipoproteinemia familiala III)
-HLP secundare
-af hepatocelulare
-colestaze
-SN, IRC, DZ
-cardiopatie ischemica
-alcoolism

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15
Q

CT scade in:

A

-necroza hepatocelulara masiva
-neoplasm hepatic
-malnutritie
-malabsorbtie

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16
Q

Lipide Totale (LS = lipide serice): VN

A

500-800 mg/dl

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17
Q

LS crescute:

A

-aport crescut
-HLP
-trat cu anticonceptionale orale
-hipotiroidism
-acromegalie
-DZ
-icter obstructiv
-SN, IRC

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18
Q

LS scazute:

A

-malabsorbtie
-hipertiroidism
-ciroza

19
Q

HDL colesterol: VN

A

b: >40 mg/dl
f: >50 mg/dl

20
Q

HDL < 35 mg/dl

A

risc coronarian crescut

21
Q

LDL colesterol: VN

A

<130 mg/dl

22
Q

Lipidograma normala: LST

A

500-800 mg/dl (700)

23
Q

Lipidograma normala: CT

A

200 mg/dl

24
Q

Lipidograma normala: TG

A

115 mg/dl

25
Q

Lipidograma normala: PL = fosfolipide

A

200 mg/dl

26
Q

Lipidograma normala: AGL = acizi grasi liberi

A

0.5 uEq/l

27
Q

ELFO: alfa LP = HDL

A

25-35%

28
Q

ELFO: pro beta LP = VLDL

A

10-15%

29
Q

ELFO: beta LP = LDL

A

50-60%

30
Q

ELFO: chilomicroni

A

2%

31
Q

ELFO: aspectul plasmei racite

A

clar

32
Q

HLP I = Deficit familial LPL

A

TG + (hipertrigliceridemie)
chilomicronii +

33
Q

HLP IIa = hipercolesterolemie familiala

A

CT + (hipercolesterolemie)
LDL +

34
Q

HLP IIb = hiperlipidemie familiala

A

CT +
TG +
VLDL +
LDL +

35
Q

HLP III = disbetahiperlipoproteinemie

A

CT +
TG +
IDL +

36
Q

HLP IV = hipertrigliceridemie familiala

A

TG +
VLDL +

37
Q

HLP V

A

TG +
VLDL +
chilomicronii +

38
Q

HLP VI

A

Hipercolesterolemie moderata
HDL +

39
Q

HLP sec din DZ

A

tip 1: -controlat LST normal
-necontrolat: TG+ ; CT+ ; VLDL+ ; LDL+
tip 2: TG+ ; VLDL+ ; HDL-

40
Q

HLP sec din hipotiroidism

A

VLDL +
LDL +

41
Q

HLP sec din alcoolism cronic

A

AGL + !!!
TG +
VLDL +

42
Q

HLP sec din SN

A

LDL +
VLDL +
TG +

43
Q

HLP sec din IRC

A

TG +
VLDL +
HDL +
(HLP tip IV sau V)