Megaloblastic anaemia Flashcards
1
Q
What is megaloblastic anaemia caused by
A
Lack of either B12 or folic acid
2
Q
What is another cause of megaloblastic anaemia
A
Pernicious anaemia - malabsorption of B12
3
Q
How long is folic acid given for in this situation
A
Given for 4 months until stores are replenished
4
Q
What B12 is given to treat it
A
Hydroxocobalamin is the choice of therapy - retained in the body longer than cyanocobalamin and thus requires fewer dosing intervals
5
Q
What is given in folate deficient megaloblastic anaemia with cytotoxic drugs
A
Folinic acid - given as calcium foliate
6
Q
What is megaloblastic anaemia
A
Unusually large, abnormal and immature red blood cells
