MEDICINE DISEASE OF ESOPHAGUS & STOMACH

Question 1

CLINICAL FEATURES & COMPLICATION OF GERD

Answer 1

CLINICAL FEATURES
- Regurigtation of sour materian into mouth
- Heartburn
- Chronic cough
- Aspiration pneumonia

COMPLICATIONS
-ulceration
-bleeding
- barret’s oesophagus

Question 2

CLINICAL FEATURES AND MANAGEMENT OF BARRET’S ESOPHAGITIS

Answer 2

CLINICAL FEATURES
- DYSPHAGIA
- REGURGITATION
- EPIGASTRIC PAIN
- WEIGHT LOSS

MANAGEMENT
- SEDATIVES
- DRUGS REDUCING LES PRESSURE (ANTICHOLINERGIC//CALCIUM CHANNEL BLOCKER)
-SURGERY

Question 3

CLINICAL FEATURES OF DUODENAL ULCER & GASTRIC ULCER

Answer 3

DUODENAL ULCER
- 1st part duodenum
- High gastric acid
- food reliefs pain

Gastric Ulcer
- lesser curvature
- Low gastric acid
- Food triggers pain

BOTH
*abdominal pain
*nausea & vomiting

Question 4

MANAGEMENT PEPTIC ULCER DISEASE

Answer 4

1. ACID NEUTRALIZING // INHIBITORY DRUGS
   
   • Antacids
   • H2 receptor blocker
   • PPI
2. Cytoprotective agent
   
   • sucralfate
   • bismuth subcitrate
3. Prostaglandin analogues
   -misoprostol

Question 5

COMPLICATION OF PEPTIC ULCER

Answer 5

• CHRONIC IRON DEFICIENCY
• UPPER GASTROINTESTINAL BLEEDING
• PERFORATION (duodenal cap)
• PANCREATITIS

Question 6

CAUSES & PREVENTION OF STRESS-RELATED MUCOSAL INJURY

Answer 6

CAUSES
-Sepsis
-Severe trauma
-Head injury
-Severe burns

PREVENTION
*H2 blocker
*Sucralfate suspension
*Intra-arterial vasopressin