medications

Question 1

What medication is used in “single antiplatelet therapy?

Answer 1

Aspirin

Question 2

What medications are used in “dual antiplatelet therapy?

Answer 2

Aspirin and clopidogrel

Question 3

What is the MOA of dopamine?

Answer 3

It stimulates alpha and beta1 adrenergic and dopaminergic receptors producing inotropic, chronotropic, renal/ splanchnic vasodilaory (at low doses), and pressor (at high doses) effects.

Question 4

What is the generic name for Levophed?

Answer 4

noreepinephrine

Question 5

What is the MOA of norepinephrine?

Answer 5

It acts on both A1 and A2 adrenergic receptors to cause blood vessel contraction. This thus causes a resultant increase in peripheral vascular resistance. It is a sympathomimetic drug used to treat patients in vasodilatory shock states such s septic or neurogenic shock, while showing fewer adverse side effects compared to dopamine.

Question 6

What is another name for norepinephrine?

Answer 6

What is another name for noradrenaline?

Question 7

Which PPI cannot be used with clopidogrel and why?

Answer 7

Omeprazole, because studies have found a significant decrease in the platelet antiaggregation effect of clopidogrel when used concurrently with omeprazole. These effects were not sen with pantoprazole.