Mediated transport Flashcards
Extracellular matrix; ECM
Secreted by cell
A variety of supported and adhesive proteins
Embedded inn a gel composed of polysacharrides that are linked together by different proteins
Provides biochemical support function (such as those provided by proteins called growth factors which promotes cell survival and growth)
ECM in plant cells
ECM is the cell wall, which is composed mainly of overlapping cellulose fibers
Plant cell walls protect and support each call and attatch adjacent cells to one another
The walls are porus and allow O2, CO2 & H20 containing dissolved substances to flow through them
How do membrane glycoproteins allow recognition between cells
Attatched carbohydrates are identification tags that are recognized by membrane proteins in other cells
Facilitated diffusion
Type of mediated transport
It goes down the electrochemical gradient downhill from HIGH -> LOW
(Faster rate than would occur with passive diffusion)
Active transport
Type of mediated transport
An uphill flux AGAINST an electrochemical gradient
Uphill from LOW -> HIGH
A moving solute against its concentration gradient (cell must expend energy)
Membrane permeability to Cl-
Is permeable
Membrane permeability to Na+
Not permeable :(
Na/k+ATPase pump steps
- Binding of 3 NA+ Ions
- Binding of ATP & reaction to release energy
- Conformational change; Translocation of NA+
- NA+ released; Binding of Potassium (K+)
- Hydrolysis; Release of Phosphorus (P)
- Conformational change; Transport of potassium (K+)
- Release of Potassium (K+)
Carries sodium out of cell & potassium into cell
(Requires energy)
Passage of salt (NaCl) across plasma membrane
Primary importance in cells
The chloride ion (CL-) usually crosses the plasma membrane because it is attracted to positively charged Na+ ions
- Na+ ions are pumped across the membrane by active transport
- Cl- ions simply diffuse through channels that allow their passage
Cystic fibrosis
Cl- channels (channel proteins) malfunction in persons with cystic fibrosis
A thick mucus collects in airways & in pancreatic and liver ducts as a result
How is each ion subject to 2 forces
- Transport in one direction
- Offset by diffusion in the other direction
Why bacteria die when you take antibiotics
Osmosis into the hypertonic cytosol of the bacterium will cause the bacterial cell to swell and rupture its fragile plasma membrane
Which is fatal (Bacterium dies)
Rip my man bacteria he aint do nothin wrong.
Bulk transport
Biological processes that allows the movement of large quantities of substances across cell membranes and through organism.
There are various modes of bulk transports:
- Exocytosis
- Endocytosis
Endocytosis
Particles or liquids surrounded by a unit membrane and incorporated into a cell
Imports substances by forming vacuoles/vesicles
Phagocytosis - cellular eating
Pinocytosis - cellular drinking
Receptor mediated endocytosis - highly selected process
Exocytosis
Transfers macromolecules out of the cell
exports bulky molecules such as proteins and polysacharrides