MCBG - How To Remember Collagen Formation Flashcards
1
Q
What is the acronym for remembering collagen formation?
A
CHAD POGRL
2
Q
What does C stand for?
A
Cleavage of signal peptides
3
Q
What does H stand for?
A
Hydroxylation of proline and lysine (by prolyl/lysyl hydroylase)
4
Q
What does A stand for?
A
Addition of N-linked oligosaccharides and galactose (in ER)
5
Q
What does D stand for?
A
Disulphide bridge formation
6
Q
What does P stand for?
A
Procollagen sent to Golgi
7
Q
What does O stand for?
A
O-linked glycosylation (in Golgi)
8
Q
What does G stand for?
A
Golgi - exocytosis as tropocollagen
9
Q
What does R stand for?
A
Removal of N/C terminal peptides by (procollagen peptidase)
10
Q
What does L stand for?
A
Lateral aggregation to form fibrils
