Mandelian Inhertance Flashcards
Gregor Model 2 discoveries
Segregation
Independent assortment
Deals with the manner in which genetic differences are passed generation to generation.
Favourable characteristics
Early transmission genetics
Who believed in blending inheritance?
Charles Darwin
Blending inheritance suggested that…
Variation is lost over time
Problem with blending inheritance is…
Rare variants will have no opportunity to increase frequency even if they survive
Mendel proved…
Traits are no transmitted, genes are
Physical appearance in each successive generation is identical to the last
True breeding
First offspring
F1
F1 self-fertilised
F2
Can be used for testcrossing to learn unknown genotypes
Punnetr squares
Phenotype of the heterozygous genotype is intermediate between those homozygous
Incomplete dominance
Pigment expression (eg) due to chromosomes.
Epistatis
Pedigrees in human is more difficult than peas…
We don’t choose our mating partners for convincence of biologists
Number of children in families are small
Genotype corresponding to a trait does not show in the phenotype
Incomplete penetrance
Proportion of environment or other gene interaction less than 100%
Penetrance