Male Reproductive Flashcards
What are the 4 stages of spermatogenesis?
Spermatocytogenesis, meiosis, spermiogenesis, spermiation
How many chromosomes does a mature sperm have?
23 (22 autosomes and 1 sex chromosome)
What cells are in the basal compartment of the seminiferous epithelium?
Spermatogonia and part of sertoli cells
What cells are in the adluminal compartment of the serminerous epithelium?
Primary spermatocytes, secondary spermatocytes, early spermatids, late spermatids
What regulates Sertoli cells after puberty?
FSH
What do Sertoli cells secrete?
Inhibin, which exerts a negative feedback on FSH and activin, which has a positive feedback action on FSH
What do Leydig cells make and where are they located?
Testosterone. Intertubular space.
What is the wall of the seminiferous tubule made of?
Peritubular hyoid cells and fibroblasts
What cells are the permentant somatic components of the serminiferous tubule epithelium?
Sertoli cells
What are the basic steps of the spermatogenic cycle?
Stem cell renewal, mitotic amplification, meiosis I, meiosis II, spermiogenesis, spermiation
What is a characteristic feature of spermatogenesis?
Incomplete cytokinesis and cell cycle synchrony. Cells are joined by cytoplasmic bridges until completes of spermatogenesis
What forms the blood-testes barrier? What does it divide?
Tight junctions between Sertoli cells. Separates the spermatogonia in the bass compartment from the spermatocytes and spermatids in the adlumina compartment
Where do sperm gain motility?
In the epidydimus
