M4 L2 Flashcards
1
Q
complement is always in
A
blood & ECF
2
Q
complement is apart of which type of immune system?
A
both- innate & adpative
3
Q
innate immune response cascade steps
A
1) pathogens enter beyond first line defense
- ex. pathogen broke physical barrier
2) pattern recognition receptors activated on immune cells (neutrophils) and non-immune cells (epithelial cells)
3) release of inflammatory mediators
ex. eicosanoids, cytokines, chemokines & histamine
4) vasodilation through capillary wall
5) C3 breaks apart to C3A & C3B
6) bring more complement & cells to cite of infection
7) fever, pain & appetite suppression
