Lung Fibrosis

Question 1

What is the approximate surface area used for gas exchange?
A. 1m^2
B. 15m^2
C. 65m^2
D. 115m^2

Answer 1

C. 65m^2. Everything that is breathed in hits this surface area

Question 2

On a daily basis how much air do you breathe in?
A. 500L
B. 1,500L
C. 10,000L
D. 27,000L

Answer 2

C. 10,000L. Your tidal volume, the amount you breathe in each time, is about 0.5L. This equates to about 10,000L overall.

Question 3

On a daily basis, how many viruses do you breath in?
A. 5,000
B. 5,000,000
C. 500,000,000
D. 5,000,000,000

Answer 3

C. 500,000,000. However, not all of them are human.

Question 4

On a daily basis how many bacteria do you breath in?

Answer 4

5 million

Question 5

What class of MHC would be important for generating antibodies?

Answer 5

MHC2

Question 6

What class of MHC would be important for cell-mediated cytotoxicity?

Answer 6

MHC1

Question 7

Which subset of T lymphocytes would promote a cytotoxic T cell response?

Answer 7

Th1

Question 8

What is the order of biomechanical events during an active breathing cycle (in then out)?
A. Internal intercostals contract, diaphragm contracts, external intercostals contract, diaphragm relaxes
B. Diaphragm relaxes, external intercostals contract, diaphragm contracts, internal intercostals contract
C. Diaphragm contracts, external intercostals contract, diaphragm relaxes, internal intercostals contract
D. Diaphragm contracts, external intercostals relax, diaphragm relaxes, internal intercostals contract

Answer 8

C. Diaphragm contracts, external intercostals contract, diaphragm relaxes, internal intercostals contract

Question 9

What is the usual order of events during tissue repair/wound healing?
A. Inflammation, Haemostasis, Remodelling, Proliferation
B. Haemostasis, Inflammation, Proliferation, Remodelling
C. Proliferation, Haemostasis, Inflammation, Remodelling
D. Haemostasis, Proliferation, Inflammation, Remodelling

Answer 9

B. Haemostasis, Inflammation, Proliferation, Remodelling

Question 10

During aberrant wound healing (lung fibrosis), which cells types are important?
A. Epithelium
B. Macrophages
C. Fibroblasts
D. Myofibroblasts
E. Endothelial cells
F. All of the above

Answer 10

F. All of the above