Lung cancer

Question 1

TNM8 Staging

Answer 1

T1a <1cm
T1b 1-2cm
T1c 2-3cm

T2a 3-4cm
T2b 4-5cm
BVL: bronchial wall, visceral pleura, lobe collapse/atelectasis/pneumonitis

T3 5-7cm
OR 1 or more tumour in same lobe
OR involvement of PPPC: parietal pleura, phrenic nerve, pericardium, chest wall

T4 >7cm
OR 1 or more tumour different lobe ipsilateral lung
OR involvement VOLTC DM: vertebral body. oesophagus, laryngeal nerve, trachea, carina, diaphragm, mediastinum

N1 - ipsilateral peribronchial / ipsilateral hilar LN / IPLN
N2- ipsilateral mediastinal, subcarinal LN
N3 - contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene or supraclavicular LN

M1a - separate tumour nodule in contralateral love, pleura, pericardial nodules, pleural or pericardial effusions
M1 b - single extra thoracic metastasis
M1c - multiple extra thoracic metastases in 1 or more organs

Question 2

Lung cancer staging

Answer 2

Question 3

Survival rates for NSCLC

Answer 3

Stage I: 88% (1 year), 56% (5 year)
Stage II: 73% (1 year), 34% (5 year)
Stage III: 52% (1 year), 13% (5 year)
Stage IV: 19% (1 year), 3% (5 year)