LMR Flashcards

1
Q

Osteoporosis risks

A

-caffeine, smoking
-lack of weight bearing exercises
-lack diet rich in Ca and Vit D

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2
Q

What is increased in rheumatoid arthritis?

A

Erythrocyte Sedimentation Rate

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3
Q

What labs should you check with/ macrocytic normochromic anemia?

A

Vitamin B12 and Folic Acid

(Note: this is a severe form of anemia, RBCs larger than should be

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4
Q

What is increased in autoimmune disorders?

A

Cytokines
(Proteins that effect the immune system)

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5
Q

Disseminated encephalomyelitis S/S?

A

Weakness, paresthesia, *asymmetrical body movement (extremities)
- do neuro exam, this is a neuro d/o w/ inflammation in brain and spinal cord- damages myelin

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6
Q

Clozapine is metabolized by____?

A

CYP1A2* and CYP2B6

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7
Q

Limbo system includes:

A

Amygdala, Hippocampus, thalamus, hypothalamus, basal ganglia, anterior cingulate gyrus

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8
Q

Where is Ach synthesized?

A

Basal nucleus of Meynert

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9
Q

Meds that cause Depression

A

Steroids, beta blockers, interferons, isotrenitoin (Accutane), some retroviral drugs, antineoplastic drugs, benzos, progesterone

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10
Q

Lithium S/E

A

Hypothyroidism, fine hand tremors, GI upset (cramps, V/D, anorexia) diabetes insipidus, polydipsia, polyuria, t-wave inversion, maculopapular rash, Leukocytosis

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11
Q

Lithium toxicity

A

Severe N/V/D, coarse hand tremors, muscle weakness, ataxia, heart palpitations

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12
Q

Drugs that reduce renal clearance

A

NSAIDS, thiazides, ACE inhibitors

-increases concentration of drugs cleared by kidney like lithium

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13
Q

Lithium can be increased due to ___ and _____

A

Hyponatremia and dehydration

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14
Q

Signs of hepatotoxicity

A

RUQ pain, reddish brown urine, yellowing of skin/whites of eyes, fatigue

-if taking depakote: DC depakote and check LFT

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15
Q

Signs of depakote toxicity

A

N/V, lethargy, disorientation, respiratory depression

-DC depakote, check serum dep levels, LFTs and ammonia

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16
Q

S/S pancreatitis

A

Fever, tachy, N/V/ oily stools
Upper abd pain, abd pain radiating to back, tender abd w/out touch

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17
Q

Aplastic anemia s/s
(Stop producing new blood cells)

A

Pallor, fatigue, SOB, HA, fever, skin rash, bleeding gums, nose bleed

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18
Q

S/S infection

A

Sore throat, sudden fever, chills, weakness

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19
Q

Alpha delta 2 ligands

A

Gabalin and pregabalin - can use for chronic pain w/out depression

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20
Q

Labs NMS

A

Increased CPK, LFTs, WBCs (leukocytosis) and myoglobinuria

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21
Q

Tx NMS

A

DC offending agent first
Bromocriptine (Parlodel) =D2 agonist
Dantrolene (Dantrium) = muscle relaxant

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22
Q

3 meds that delay gastric emptying

A

Omeprazole, famotidine, ranitidine

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23
Q

Negative symptoms of schizophrenia

A

Affective flattening, avolition, alogia, anhedonia, apathy, attention deficits, abstract thinking probs

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24
Q

DMDD med for severe irritability

A

Ritalin

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25
Q

Signs of stimulant abuse

A

Insomnia, tremor, heart palpitations, Anxiety, Agitation, irritable, mood swings, increased HR and BP,

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26
Q

What med for delirium agitation /psychosis

A

Low dose Haldol

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27
Q

Check what labs of suspect dementia?

A

B12 and folic acid

28
Q

Inducers

A

Carbamazepine, tobacco, phenobarbital, phenytoin, St John’s Wart

29
Q

Inhibitors

A

Grapefruit, SSRIs, bupropion, cimetidine, clomipramide, clarythromycin, fluoroquinolones, nefazodone, kentoconazole,

30
Q

Meds contraindicated with MAOIs

A

Meperidine, decongestants, TCAs, stimulants, atypicals, St. John’s wart, asthma meds, l-tryptophan

31
Q

HTN crisis S/S

A

Fever, occipital HA, flushing, sweating, dilated pupils, increased BP

32
Q

HTN crisis tx

A

DC med
phentolamine- brings BP down
Stabilize fever

33
Q

S/S lead poison

A

Development delay, learning difficulties, loss of appetite, weight loss, irritable, sluggish/fatigue, abd pain, V, constipation, hearing loss, pica, seizures

34
Q

Tx EPS except TD

A

Benztropine (Cogentin)

35
Q

Subcortical

A

Lack coordination, ataxia, tremors, dystonia

Huntington’s, Parkinson’s, HIV

36
Q

Cortical

A

Language (aphasia) and memory (amnesia)

Alzheimer’s and Creutz-feldt Jacob

37
Q

Early signs HIV dementia

A

Motor (dystonia, tremors, ataxia, loss coordination), cog decline, behavior

38
Q

Hallmarks vascular dementia

A

Carotid bruits, fundoscopic abnormalities, enlarged cardiac chambers

39
Q

1st line pts psychotic symptoms with dementia

A

Nonpharm first, then
Atypical antipsychotics
NO BZNz

40
Q

COWS

A

N/V/D, muscles aches, insomnia, yawning, piloerection, dilated pupils, anxiety/ irritable, lacrimation, rhinorrhea, sweating

41
Q

Cows start tx at?

A

7, clonidine
>13 give SL suboxone or buprenorphine

42
Q

CIWA

A

Tremor, paroxysmal sweating, anxiety, agitation, HA, audio/visual/tactile distortions, N/V

43
Q

CIWA start tx at?

A

8, PRN only
>15 scheduled and PRN

44
Q

Tx ETOH

A

Disulfiram, acamprosate, naltrexone

Residential Tx

45
Q

Perjury

A

Lying under oath

46
Q

Perjury

A

Lying under oath

47
Q

Rights of pt

A

Least restrictive environment, informed consent, confidentiality

48
Q

4 components health policy

A

Process, policy reform, policy environment, policy makers

49
Q

Rennie v Klein

A

Right to refuse psychotropic meds

50
Q

Rennie v Klein

A

Right to refuse psychotropic meds

51
Q

Tarasoff

A

Duty to warn, diff per state, check with state BON

52
Q

Suicide risk factors

A

Male >45, female >55, male, white, single/divorced/separated, living alone, psych or physical illness substance abuse, previous suicide attempt, fam hx suicide, recent loss

53
Q

Greatest risk bipolar

A

Fam hx across multiple generations

54
Q

Med approved for bulimia

A

Prozac

55
Q

Anorexia s/s

A

Low BMI, emaciated, amenorrhea, bradycardia, hypotension, t-wave inversion, prolonged QT interval

Hospitalize if BMI <15

56
Q

S/s discontinuation syndrome SSRI

A

Flu-like: fatigue, lethargy, myalgia, N/V, decreased concentration, impaired memory, paresthesias, shock-like sensations, anxiety, irritable, insomnia, crying, dizzy

Occurs 24-72 hrs, resolve 1-14 days

57
Q

Contraindications ECT

A

Heart disease, compromised pulmonary status, hx head injury/tumor, anesthesia complications

58
Q

Adverse effects ECT

A

Arrhythmias, headache, drowsiness, myalgia, memory disturbance, confusion

59
Q

Labs in ETOH

A

Increased GGT, MCV, PT, uric acid, total cholesterol, triglycerides

AST/ALT ratio greater than 2

Decreased Ca, Mg, K, BUN, albumin, platelets, hematocrit, hemoglobin

60
Q

4 dimensions recovery

A

Health home purpose community

61
Q

Increased ach

A

Teary eyes, salivation, diarrhea

62
Q

Other med that can cause EPS

A

Metoclopromide (Reglan)

63
Q

Serotonin syndrome Tx

A

Cyrpoheptadine

64
Q

SS Tx

A

Cyrpoheptadine

65
Q

Other med that causes SS

A

Triptans like sumitriptan (imitrex)

66
Q

FDA approved panic d/o

A

Prozac, Paxil, Zoloft
Effexor

67
Q

Pharm Tourette’s

A

Atypicals
Haldol, Pimozide, abilify
Guanfacine/clonadine for impulse/rage control
SSRI