Liver function Flashcards
3 key risk factors for liver disease
NAFLD, alcoholic liver disease, hepatitis C
7 risk factors for alcoholic liver disease
Alcohol dependence, female, overweight, african, genes, drinking pattern, hepatitis C
Why is management of obesity key in hepatitis C treatment?
Obesity can reduce effectiveness of antivirals
PEM can lead to 6 consequences (MAEVIR)
Mortality Ascites worse Encephalopathy Variceal bleeds Infections Re-admission
How can ascites act to worsen PEM?
Early satiety as the pressure results in lower gastric capacity
Why could you lose your appetite?
Cytokines
3 causes of nausea and vomiting related to liver disease?
Gastropariesis, small bowel dysfunction, bacterial overgrowth
Why can alcohol worsen PEM?
B vitamin deficiency, nutrient replacement
Taste changes can be caused by deficiency in which 2 nutrients?
Zinc and magnesium
Why may zinc and magnesium deficiency occur?
Reduced availability of magnesium; protein metabolism affects zinc plasma transport
Key signs of zinc deficiency (IRA Wants Help)
Immune impairment, Rash worse, Appetite change, Wound healing, Hair loss
Why is magnesium deficiency not usually related to intake?
Excretion is tightly controlled by kidneys
Key signs of magnesium deficiency (My Cramps Are Annoying)
Muscle spasm, Cramps, Arrhythmia, Appetite loss
Hypomagnesaemia can be caused by excess ____
hypercalcaemia
Hypomagnesaemia can lead to secondary deficiency of which two other micronutrients?
Potassium and calcium